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439539 tn?1233465815

4 Wk. PCR Results ! ????????

I got my 4 wk. PCR results ! I just got home and don't want to look up and figure out.Dropping o's etc.Thank you for looking ! Thank You !       My start viral load was       772575     5.89 H
HEPTIMAX   (R)   HCV   RNA        Out of range 122000   H       < 5  IU/mL          
HEPTIMAX   (R)   HCV   RNA        Out of range 5.09       H       < 0.70  log  IU/mL
By the way my HGB went from  9.8 from the 3rd. to 11 today ! I can breath better !
Thank you before hand.
Tammy
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439539 tn?1233465815
First of all, I know you are busy but yet you took the time to make sure I had the links to prove what I say.You are one caring person to do that as are the others.Thank you so much.
Yes, rheumy Dr. did do the urine culture and antibiotics was then started.I had been fighting with my first uti for eight or so months.
My primary was told several times and done cultures.He said, go home, drink lots of OJ and you'll be fine.
It was my rheumy who found ALL the things wrong with me.I have very high respect for the woman.I found out in Nov. of 07.She put me on a generic for ocycotin.It was helping with the pain.two months and Ins. said, no we won't cover that anymore but did approve morphine.I had been taking ten months prior to starting Peg-Intron.
Last visit with her she told me next appt. we will talk about Enbrel.
Yes she did tell me about the autoimmune problems I may be facing but I really don't think she knows about the morphine.I may be wrong, but I copied all the links you gave me and have a package for her on Monday morning.Thanks to you, she will know ! She has to change the morphine or take me off asap.I guarantee if she didn't know, she will be ON IT.
Blood pressure.I haven't monitered the numbers lately, but when I do the Benicar has it stabalized.It was borderline to start with three yrs. ago.I keep asking primary to change it or take me off.I'm due to see him before next re-fill at first of month.
I have to self cath because of a radical hysterectomy thirteen yrs. ago.I think that was the cause for uti.I di trust my Drs.and I'll copy and print your latest links.I have to run to the store before they close so I will continue in a little minute.
Tammy
Helpful - 0
276730 tn?1327962946
Wishing you well!!!!!!!!!!!!
Helpful - 0
568322 tn?1370165440
I am hoping your doctors told you that Hep C treatment can cause severe rheumatoid arthritis flare ups and they'll be watching you closely.

Because if they didn't tell you then they'll have nothing on the list of "Things done right"....and you deserve better than that.  

Co
Helpful - 0
568322 tn?1370165440
"WBC  was 12.1 out of range."

"I have never had staph.My husband say's I've always been the healthiest person he knows.Untill all this."
-------------------------------

The UTI would have caused the high white cell count (WBC).

The result from the urine culture (I hope they did one) would tell you whether the UTI was caused by staph (which is very common) or by something else.



"Rheumy started tx with morphine for RA because I was going to start tx."
----------------------------

I have seen people who had been taking Morphine for a long time reach SVR.  But starting the Morphine at the SAME TIME as treatment was probably not the best move.



"Should I ask to be taken off the morphine ? It doesn't seem to be helping anyways."
------------------------------
Do not stop taking it on your own because stopping Morphine can also increase the viral load.  Discuss it with your Rheumatologist (show him the studies on Morphine from the two links I gave).  If he decides to stop it he may want to decrease it slowly.  



"I'm sorry, unless it's on on of my two CBC's I don't have a fasting blood sugar level."
-----------------------------

They must have done it at baseline.  It's usually done on the same test that checks your liver enzymes.  And I doubt they would have started treatment without checking the liver enzymes.  From now on, make sure you get a copy of all your blood work.  There are lots of eyes in this forum that can help you spot problems.



"Looking at my standing order for blood draws I noticed,
Week 12-before 13th injection   CBC, CMP, TSH  I won't have that Comprehensive Metabolic Panel until then."
------------------------------

You can't wait that long.  You see... insulin resistance is frequent in people who have rheumatoid arthritis.  Multiple studies have shown that fasting insulin levels and HOMA test (which checks for insulin resistance) scores were significantly higher in all patients with rheumatoid arthritis.  

http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijrh/vol1n1/tnf.xml


Make sure you remind your doctors of that.  Looks like they may have forgotten.  Plus, you also have high blood pressure....also linked to insulin resistance.  They need to take care of it now to give you a better chance of SVR.  

Let me give you some links to studies that will show them why testing for, and treating insulin resistance is so important, just in case you have to convince them.  The first study talks about insulin resistance causing extra insulin to be produced.....and having too much insulin makes interferon ineffective.  

I commend you for your proactive approach and positive attitude.  You can do this.  Let me know if there's anything else I can do to help.

Co


"interferon alpha blocks HCV replication. However, when insulin (at doses of 128 microU/mL, similar that seen in the hyperinsulinemic state) was added to interferon, the ability to block HCV replication disappeared"

http://scielo.isciii.es/scielo.php?pid=S1130-01082006000800006&script=sci_arttext


"Insulin-Resistance in Chronic Hepatitis C patients: New Predictor of Sustained Virological Response Independent of HCV Genotype and Liver Fibrosis Stage."

http://aasld.scientificposters.com/epsAbstract.cfm?id=37


"Glucose >100 mg/dl Reduces Interferon/RBV SVR"

http://www.natap.org/2008/HCV/031008_01.htm


"Therapies to Manage Insulin Resistance Improve Response to Interferon-based Therapy in Chronic Hepatitis C Patients."

http://www.hivandhepatitis.com/2008icr/aasld/docs/112108_a.html
Helpful - 0
439539 tn?1233465815
Looking at my standing order for blood draws I noticed,
Week 12-before 13th injection   CBC, CMP, TSH  I won't have that Comprehensive Metabolic Panel until then.
Tammy
Helpful - 0
439539 tn?1233465815
Like I said, if it was easy, everyone would tx.Look at what you've been through.You didn't have the heart to tell me.That was sweet of you.I have to go to work.I'm going to print out the links CoWriter sent, take them to my hep and rheumy.I'll take it from there.
Rheumy had me on Methotrexate and oxycotin before tx.Insurance would not pay for the generic oxycotin so they agreed to pay for morphine.We dropped the methotrexate but kept me on morphine for the rheumatoid arthritis.
I took riba this morning but am waiting awhile to take others.It probably doesn't matter.
It'll all work out in the end.Tonight is 6th. injection.I'll find a way.
Again thank you to ALL !
Tammy
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