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86075 tn?1238115091

Another New Drug in Trial

Dutch biotechnology firm OctoPlus said on Tuesday European safety and efficacy Phase IIa studies have shown an antiviral effect for its chronic hepatitis C drug Locteron.

"A statistically significant dose response was observed in the study," the company said in a statement, adding that the drug was tolerated at all doses.

The company, which has four other products in pre-clinical and clinical development, said approximately 90 percent of adverse events were rated as mild.

OctoPlus is co-developing Locteron with its partner Biolex Therapeutics, which plans to commence a European safety and efficacy Phase IIb trial of the drug in mid-2008.

With Locteron, OctoPlus is aiming to develop a treatment for patients with chronic hepatitis C, with fewer side effects and a more convenient dosing schedule compared with current therapies.
4 Responses
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276730 tn?1327962946
Thanks alot for posting that, It is interesting......and eventually something has got to give. :}






Helpful - 0
86075 tn?1238115091
so good to see you! hope youre doing well....yeah, they seem to be throwing more firepower toward this dang little bug....so many new things happening....
Helpful - 0
85135 tn?1227289772
Thanks for posting about a new Hep-C drug in the pipeline. It gives one hope that this nasty virus can be eliminated in the near future.
I have to give a chuckle about “a more convenient dosing schedule”. That was on the bottom of the complaint list as far as a “cure” was concerned when I treated.

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Avatar universal
That's very interesting. Gives the newbies hope.
Helpful - 0

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