Aa
Argument with Dr..
Good morning.. I have been slacking around here, but have been sooo busy..Having wood floors put in two rooms in my house.. Damn, what royal pain!!
Yesterday, I went to my GI center.. Did all the baseline bloodwork done, went over expected approach, preventional use of meds to stay on tx, and all lab work.. They will be doing blood, first 2 weeks, then 2 weeks after that, then every month following.. Only doing pcr, at 12, and 24 weeks.. I had to fight for pegysus.. Told me that I was crazy, that sx's are the same, percentages are the same, and that the leaders in treating hep c, won't even touch pegysus.. Supposedly, Dr. Schiff from the Liver Institute in Miami, won't even touch pegysus..She told me that if it what I want, she would order it, but it is not her first choice..
Has anyone else come across this with their DR.??
I also lucked out, and she gave me three month supply of Effexor samples for free..She wanted to do a phycological evaluation on me, before tx.. I told her fine, but I would have to talk it over with the voices in my head!! LOL..
Looks like I'll be starting here in the next two or three weeks.. She told me, to use Benadryl, and Tylenol PM, and Zyrtec for sides.. Gauranteed to do evrything possible to get me through.. Wanted to make sure I was ready for it, and feet where firmly planted.. How could I say no to such a beautiful woman??
Yesterday, I went to my GI center.. Did all the baseline bloodwork done, went over expected approach, preventional use of meds to stay on tx, and all lab work.. They will be doing blood, first 2 weeks, then 2 weeks after that, then every month following.. Only doing pcr, at 12, and 24 weeks.. I had to fight for pegysus.. Told me that I was crazy, that sx's are the same, percentages are the same, and that the leaders in treating hep c, won't even touch pegysus.. Supposedly, Dr. Schiff from the Liver Institute in Miami, won't even touch pegysus..She told me that if it what I want, she would order it, but it is not her first choice..
Has anyone else come across this with their DR.??
I also lucked out, and she gave me three month supply of Effexor samples for free..She wanted to do a phycological evaluation on me, before tx.. I told her fine, but I would have to talk it over with the voices in my head!! LOL..
Looks like I'll be starting here in the next two or three weeks.. She told me, to use Benadryl, and Tylenol PM, and Zyrtec for sides.. Gauranteed to do evrything possible to get me through.. Wanted to make sure I was ready for it, and feet where firmly planted.. How could I say no to such a beautiful woman??
One quick comment. Almost ALL industries are involved in some type of rebate programs with vendors. The medical industry in no exception. Trucking, travel, food, just about all of them. This is the way of accounting. My regular doctor and I are very good friends. The stories he has told me about drug companies and their efforts to get doctors, hospitals and HMOs to go their way is mind boggling. But the reality is it is no different or worse in the application to other industries. Because it deals directly with sick people makes it morally incorrect more disgusting But
This is the final paragrphs of a meta -anlysis provided for the FDA re-the most frequently prescribed ADs. If you want the rest look for "The Emporers New Drugs".
To summarize, the data submitted to the FDA reveal a small but significant difference between antidepressant drug and inert placebo. This difference may be a true pharmacological effect, or it may be an artifact associated with the breaking of blind by clinical trial patients and the psychiatrists who are rating the severity of their conditions. Further research is needed to determine which of these is the case.
In any case, the difference is relatively small (about 2 points on the HAM-D), and its clinical significance is dubious. Research is therefore needed to assess the additivity of antidepressant drug and placebo effects. If there is a powerful antidepressant effect, then it is being masked by a nonadditive placebo effect, in which case current clinical trial methodology may be inappropriate for evaluating these medications, and alternate methodology need to be developed. Conversely, if the drug effect is as small as it appears when drug/placebo differences are estimated, then there may be little justification for the clinical use of these medications. The problem, then, would be to find an alternative, as the clinical response to both drug and placebo is substantial. Placebo treatment has the advantage of eliciting fewer side effects. However, the deception that is inherent in clinical administration of placebos inhibits their use. Thus, the development of nondeceptive methods of eliciting the placebo effect would be of great importance.
SH
To summarize, the data submitted to the FDA reveal a small but significant difference between antidepressant drug and inert placebo. This difference may be a true pharmacological effect, or it may be an artifact associated with the breaking of blind by clinical trial patients and the psychiatrists who are rating the severity of their conditions. Further research is needed to determine which of these is the case.
In any case, the difference is relatively small (about 2 points on the HAM-D), and its clinical significance is dubious. Research is therefore needed to assess the additivity of antidepressant drug and placebo effects. If there is a powerful antidepressant effect, then it is being masked by a nonadditive placebo effect, in which case current clinical trial methodology may be inappropriate for evaluating these medications, and alternate methodology need to be developed. Conversely, if the drug effect is as small as it appears when drug/placebo differences are estimated, then there may be little justification for the clinical use of these medications. The problem, then, would be to find an alternative, as the clinical response to both drug and placebo is substantial. Placebo treatment has the advantage of eliciting fewer side effects. However, the deception that is inherent in clinical administration of placebos inhibits their use. Thus, the development of nondeceptive methods of eliciting the placebo effect would be of great importance.
SH
My doc (GI) put me on Pegasys as he felt the sides were less. He stated that both types seemed to be equally efective but initial experience with patients seemed to favor Pegasys for minimal sx.
I also got almost the exact advice on use of tylenol PM and benadryl from my doc. I haven't really used the tylenol too much as I'm nervous about it's effect on the liver but the benadryl seems to help.
I sometimes get a mild hives type reaction after the shot and a half a benadryl has prevented this as well as letting me get a good night's sleep on shot night.
Silvermoon - that's too bad the benadryl makes you depressed. Its been helpful to me and I didn't think it would have an adverse effect on other folks. Goes to show how important it is not to assume anything.
Peace
I also got almost the exact advice on use of tylenol PM and benadryl from my doc. I haven't really used the tylenol too much as I'm nervous about it's effect on the liver but the benadryl seems to help.
I sometimes get a mild hives type reaction after the shot and a half a benadryl has prevented this as well as letting me get a good night's sleep on shot night.
Silvermoon - that's too bad the benadryl makes you depressed. Its been helpful to me and I didn't think it would have an adverse effect on other folks. Goes to show how important it is not to assume anything.
Peace
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