Aa
MedHelp.org will cease operations on May 31, 2024. It has been our pleasure to join you on your health journey for the past 30 years. For more info, click here.
Aa
A
A
A
Close
135456 tn?1301437624

Can anyone recomend a liver friendly antidepressant I can take when I start treatment?

I have taken wellbutrin before on treatment and stopped when my  doctor and I found out it can cause major hepatoxicity.  Any one have good results on other ones( Effexor, Lexapro, etc..)?
26 Responses
Sort by: Helpful Oldest Newest
248382 tn?1274938634
I am on 2AD which I take at nite which help me sleep and I find my moods are much more balanced.
Lexapro 20 mg and Trazadone 100 mg, each 1 x at nite before going to bed.  

My shrink wanted me to also be on Effexor but my hepatologist worked with my shrink and they came up with my current regime which is working well.  No effexor.

I tried Wellbutrin about 3 years ago and vomited quite a bit so I quickly dropped it.  I was dx at the time of Wellbutrin but was not on treatment.

Good luck.  Jenn
Helpful - 0
Avatar universal
Thanks, I guess it is part of this desease and keeping up the persverance to fight it.

I was on both, ribavarin also all three times. Had the ribo rash, pretty much did ok physically, was more emotional mental crazy for me.
First time inteferon and ribovarin, I quite it, got so depressed, second time Pegasys and ribo, that is when I went on effexor.

This time more physical, guess it is kind of like having a baby, every time is different.

I have been reading around here,  I thought I was a an expert, but I don't know half these acronymns!   :)

Yes, I had only got a small snipet of the news cast, and funny enough I had asked when I was on Pegasys if the ribovarin was weight based and they said no.  So now I am confused again! Lot's of questions for GI and nurse.

I do know on the infergen, I am on it only 3 times a week, and wish I had it everyday! I find that every shot is like is starting over,  not sure if this is weight based or just med based.  I also get nyprogean and proctrin,(epotien) (sp?)white and red  cells crashed.

Think your right though not much that isn't bad for the liver. We all react different. I just know this, that no matter how hard this is, I refuse to give up! Even if sometimes it is easier to just lay down :)

Another question please? Anyone get a viral  load test week 4? I just had one, and while my alt and ast are normal,  cbcs climbing  back up a bit thanks to the extra shots,  my viral load went from 2000000 to 8000000 add or subtract a zero as it where:>).  

Nurse said they should of waited till week 12, so not to panic yet, but anyone else have this reaction?

thanks wyn for your answer,  I just found everyone here and nice to read what I think about! Kind of not so lonely!
Helpful - 0
173975 tn?1216257775
i am so sorry to hear about your relapses, Deb.  That is tough.

Were you on pegasys and ribavarin, last time, or just the pegasys?

Weight-based treatment seems to be the norm around here and from what I understand it has more to do with the ribavarin dose.

Is that what you mean by weight-based studies?

About the wellbutrin - it seems everything can be bad for the liver but my PCP, my new gastro and several forum folk all said it's not a concern at my damage level, S1 G1.

HNY,

wyntre
Helpful - 0
Avatar universal
I am on Effexor, second time. I suffered serious depression the first and second time, first was plain old inteferon which I stopped mid course,  second time was on Pegaysus and lost it,  GI put me on Effexor and I did ok after that.  Now I have relapsed and asked to go back  on it before I started infergen. I had also read or hear that Welbutrin was  not a good thing for the liver?
Has anyone heard about a study concerning weight based treatment? I heard a brief thing on tv that it is better for relapsers?
I am Deb by the way and wish you all a HEALTHY New year!
Helpful - 0
173975 tn?1216257775
You're right about the weaning off!  Even with the low 10mg dose of prozac i was on, I had to do 2 weeks at 5, then 2 weeks at half that.

If I had felt as horrible the past 385 days as i did for the 50 or so I was completely hopeless, i would have stayed on AD'S, but I couldn't justify taking a med every day for a problem I had 15% of the time.

Like I said, the prozac WAS a life saver for those few months but given the option of taking AD'S vs. not taking them, I opt for the latter as I'm on so many meds already.

If SX becomes too unbearable again, yes, i absolutely would go back on AD's to allow me to finish TX.

Looooove your name.  :)

wyn
Helpful - 0
373023 tn?1318524578
My partner did take citralapan during his tx...Us name Celexa...it does take time to build up so give it time....He did say he felt a litte vacant first few days that feeling does pass....it does suppress your emotions but thats what its supposed to do keep you on a even keel.....only sorta downside is it reduces sexual preformance somewhat....To Zero in some people...But again its a small price to pay to get rid of a virus....Do be aware tho don`t stop any A/Ds when tx finishes wean off them over the next few months....Take Doctors advise on this....Px
Helpful - 0

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.