My mother has end-stage liver disease. My question is how much pain goes along with it? Enough to need a prescription of methadone? The reason I ask is b/c my mother has a history of drug addiction & while her liver specialist isn't prescribing the methadone to her, another physician is. She recently spent 3 weeks with me and was absolutely fine, which means her ammonia levels were normal, she was sleeping throughout the night, up most of the day, even went shopping a couple of times, - BUT, the minute she went back home and got her prescription filled (she was without methadone the entire time she was with me b/c she forgot to bring her prescription with her) the ammonia level went back up, she's been acting clumsy, slurring her words, foggy state of mind, etc..., etc... So in my mind, this is all related to the methadone. While she was staying with me, she complained about some pain; however, she wasn't moaning & groaning, and certainly didn't seem to need anything as strong as methadone. Also, she wasn't going through withdrawals from anything else, so I know she isn't taking the methadone to treat another addiction. What's your opinion?