Aa
Eyedeas or any other naysayer.......a natural substance that really works
The reason natural substances like Maitake mushroom and EGCG from green tea aren't researched or made into drugs for mass consumption is because the pharmaceutical companies are aware that THEY CANNOT PATENT A NATURAL SUBSTANCE!
nuff said
http://www.hivandhepatitis.com/2006icr/aasld/docs/111406_e.html
nuff said
http://www.hivandhepatitis.com/2006icr/aasld/docs/111406_e.html
You, unlike The Rev, sound like a rational human. The Rev behaves like a child who has missed a dose of his Ridlin.
You should be glad you had Interferon available if you have had to treat 3 times. I agree, as I am sure everyone here does, that we need a better treatment that is easier on us but that doesn't mean we should start up taking things like these mushrooms. Or collodial silver or this liver product or that one. TCM is very "in" right now, for the most part I think it is all a waste of money, BIG money. Get a load of the prices on these things. Sheesh.
I was told not to take any herbs or supplements on tx. Others say it is ok. I figure since no one really knows, I am not going to chance it. Once I am off tx, Im going to do a few things that I feel could help and at the same time not harm me.
I do read the info. you post here and I appreciate it. I try to keep an open mind.
I was told not to take any herbs or supplements on tx. Others say it is ok. I figure since no one really knows, I am not going to chance it. Once I am off tx, Im going to do a few things that I feel could help and at the same time not harm me.
I do read the info. you post here and I appreciate it. I try to keep an open mind.
Check into AHCC(active hexose correlated compound) a mushroom extract consisting of beta glucans. It has many peer reviewed studies on its ability to boost NK cells through the roof as well as putting the body in a TH1 ready state which we need to fight HCV.
welcome back rev glad to see you up to your old self again only one day after you apologized. LOL, i knew it was to good to be true. i do believe in "natural" meds/herbs to "CONTROL" & "LIMIT" damage from hcv & hbv. it will lower vl & enzymes, NOT cure the virus, but perhaps in the future. i have been doing a lot of research lately on TCM and other alternatives and will post what i come up with in the near future.
MEDICAL PROFESSIONAL
I tried to get a look at these studies, but the link as displayed gives me a dead page. ???
Fibrosis research is extremely important, in the end - aside from HCC - it is the accumulation of fibrosis that is the essence of cirrhosis. If we could halt fibrosis progression even in the face of a mildy inflammatory liver, then maybe a lot of patients even without SVR could get stabilized. Fibrosis is a dynamic process. Its speed is dependend on individual variability in the response of the stellate system to proinflammatory signals from the surrounding infiltrate.
Several antifibrotics are in development to inhibit the activation of the predominant molecular aspect -Transforming Groth Factor beta (TGFbeta) activation that controls the transformation of these stellate cells into Collagen Fiber producing myofibroblasts "Transdifferentiation". If this molecular signaling pathway / machinery is oversensitive, then we have fast fibrosers as maybe Kalio or others here, while others are fine for decades. It is clear that the best thing to reduce or halt fibrosis is removal of the inflammation causing agent - the antigens of the HCV virus. But interference with the scar forming mechanisms that perform not a very useful but a deadly function in the liver is a realistic possibility ( "antifibrotics"). Chemically synthesized new chemicals/drugs that you can patent are the logical choice for the pharma industry , since they have to go through an expensive process of testing and proving in large trial towards the FDA that these drugs actually work for this indication and not do more harm than good.These cost need to be recovered (and are often "overrecovered"). If they would use natural substances for these trials they could never recover the cost for this scientific proof and others would simply start selling the same thing after the trial publications would come out. Overall this is a problematic situation, since many good medications are not developed in a scientifically sound way while some of these " natural substances" might be better/ less toxic than the patentable chemicals.
At NGI, many trials for new drugs against HCV and other viral diseases have come our way, since we tested if they worked and we got a look into the design and had the investigator brochures with all the details. We have seen drugs like Ribozymes come and go and knew the results way before any meeting presentation. We also had - and that brings it up here - some "Oral Interferon Inducers" to test and yes they were very IFN +other cytokines inducing.
Fibrosis research is extremely important, in the end - aside from HCC - it is the accumulation of fibrosis that is the essence of cirrhosis. If we could halt fibrosis progression even in the face of a mildy inflammatory liver, then maybe a lot of patients even without SVR could get stabilized. Fibrosis is a dynamic process. Its speed is dependend on individual variability in the response of the stellate system to proinflammatory signals from the surrounding infiltrate.
Several antifibrotics are in development to inhibit the activation of the predominant molecular aspect -Transforming Groth Factor beta (TGFbeta) activation that controls the transformation of these stellate cells into Collagen Fiber producing myofibroblasts "Transdifferentiation". If this molecular signaling pathway / machinery is oversensitive, then we have fast fibrosers as maybe Kalio or others here, while others are fine for decades. It is clear that the best thing to reduce or halt fibrosis is removal of the inflammation causing agent - the antigens of the HCV virus. But interference with the scar forming mechanisms that perform not a very useful but a deadly function in the liver is a realistic possibility ( "antifibrotics"). Chemically synthesized new chemicals/drugs that you can patent are the logical choice for the pharma industry , since they have to go through an expensive process of testing and proving in large trial towards the FDA that these drugs actually work for this indication and not do more harm than good.These cost need to be recovered (and are often "overrecovered"). If they would use natural substances for these trials they could never recover the cost for this scientific proof and others would simply start selling the same thing after the trial publications would come out. Overall this is a problematic situation, since many good medications are not developed in a scientifically sound way while some of these " natural substances" might be better/ less toxic than the patentable chemicals.
At NGI, many trials for new drugs against HCV and other viral diseases have come our way, since we tested if they worked and we got a look into the design and had the investigator brochures with all the details. We have seen drugs like Ribozymes come and go and knew the results way before any meeting presentation. We also had - and that brings it up here - some "Oral Interferon Inducers" to test and yes they were very IFN +other cytokines inducing.
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