says..... I know that vrtx is quite a way from relapsing cirrhotics........ So true, And yes your decision to retreat is the best way to go. I look at my odds and know their not to great as for SVR. I figure if i don't get SVR then i need to do everything possible to at least slow the damage being done. And hope it does till maybe these new drugs hit the market. And i know we'll make it. I came in to this world kicking and screaming and hep-c will have to take me out the same way. Plus theres so many people left that i haven't drove crazy. So i have alot of work ahead of me. And i plan on being around long enough to finish the job.:)
Although I've been aware for several weeks, it's helpful in planning a strategy whenever you get information that has a confirming aspect, even though it eliminates a possibility. In my case, I know that vrtx is quite a way from relapsing cirrhotics. As a result, it makes my decision to re-tx with peg/riba less cloudy. Although I care very much about the progress for the 'next generation' of drugs I must live in the current generation.
Sounds like we agree more then disagree:) Just some people are so eager to jump in. And as you know if you don't ask or check on the what if's alot of Doctors won't sit and explain it to you. You know my stage so i hope all these new drugs work out. And in my case the sooner the better. Doing ok here and hope you are to.
If i was able to join one of these trials and wanted to i would at least wait till the end of this year. I feel by then alot more will be known on how this drug will pan out.
Should add i hope these drugs work out for everyone that has hep-c.
Vertex has structured these trials with one goal in mind. FDA approval. This is the fastest and easiest way, even with fast track drugs to get FDA approval. Its very possible that VX-950 could work as a stand alone or even with only Peg. The bundle approach ( As with most HIV drugs ) is what Vertex as well as other companys strive for. Share prices is the main goal.
Ron
Projected timeline for Vertex trials for non-responders is second half of 2007, not "early 2007" as stated in previous post.