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Incivek Anal Burning

I'm on my fifth day of Incivek and I'm already considering ending the treatment. The anal burning sensation during and after a bowel movement is nearly unbearable. I'm afraid to eat anything because I know that will cause me to have a bowel movement. It's like giving birth everytime I have a BM. Is this normal? I'm well hydrated and eating fat before taking meds. Any advice on how to make this stop?
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532827 tn?1331361028
First time post to the community. Let me endear myself to all of you by talking about my ***!

Specifically, the anal burning. My experience was the shards of glass thing starting about day 3 or 4. I know a thing or two about pain, having severed my Achille's, but this was heavy duty and I wondered how the hell I could last through treatment. The really painful craps only lasted a bit more than than a week, though -- even so, it was an eternity in my mind.

The anal burning has not returned as of the 4-week mark. I started taking a bit more than the 20 grams of fat and perhaps that helped.

Can't say how typical my experience is. But if you're going through this agony in the early stages, it may get better.

Pointer: Baby wipes, torn in half. Boudreaux's Butt Paste. Ahhh.

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Avatar universal
Hi, welcome to the forum. I understand your discomfort, I finished incevik 5 weeks ago it was uncomfortable to say the least. I did notice eating the fat as instructed did help, but it still burned. I used warm wet wipes to ease pain. I will tell you almost immediately after finishing incevik the burning subsided. I still have a little discomfort but I still have 6 more weeks of Pegasus and ribo. I wlil also tell you I did develop anemia and the Dr prescribed procrit and it did help. I hope that you could do this like the old cliche one day @ a time and finish it will make you stronger! Stay well and god bless  
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Avatar universal
15g of water soluble fiber at night ended this terrible side effect for my husband, but there is some other very good advice here as well.
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1972385 tn?1343827076
This to will pass,a common side effect with Incevek.I almost quit and I found this forum and it saved me.Keep the area clean and treated after every BM.It should clear itself up and be less painful.Use non-alcoholic baby wipes.
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1815939 tn?1377991799
Just want to add that many of us had those big red itchy circles affter the injections. They stay around for awhile too. You could try some hydrocortizone cream on them to stop the itching but I never put that cream on until at least a week after I had injected at that particular site. You may want to run it past your doctor just in case. It is always best to discuss problems with the doc or case manager.
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1815939 tn?1377991799
Yes, I think I would agree that it is the Incivek in the feces that is causing the irritation. (Welll, I am pretty sure about that since I have had no problems since being off Incivek.) Howevr, I found that the softer or the looser stools, which tend to be more frequent simply because they are passing faster, are the ones that caused me trouble. As long as I kept the stools form, I was okay and had no problem with the pain or burning. (I was one of the people who had severe internal pain when I passed those loose or soft stools. I thought I was about to pass out each time.)

Someone posted (not sure if it is in this thread) that eating more fat helped a lot to prevent the pain and burning. I know it is a lot of fat, but if it works, might be worth a try.

Of course, Huggies wipes, Prep H supp. and Prep H cream also helped as did letting the shower water run over my behind. Some use butt cream or butt balm (not sure of the name but I did see it in the pharmacy) and others use Baneal (something like that). It is in the pharmaacy too.

There are (at least) two types of problems. One is the burning at the anus but some of us also got the horrible internal pain (like crapping razor blades or shards of glass). They both stem from the feces but the solutions may be different. All the creams in the world did nothing for that shards of glass pain because the cream was on the outside and the pain was on the inside (probably from fissures caused by the burning frequent feces). I had to keep that feces firm.The suppositories helped too.

I hope you can get this under control. If you can figure out a way to stop it treatment will be much easier or, at least, a lot less painful. Not sure I could have stood that pain for 12 weeks solid. So try a few things and hopefully you can get rid of the pain, at least.  

By the way, welcome to the forum.

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