Aa
Interfergen
Hello to all. I am 1b and will start Pegasus/Copeg very soon. I have seen Interfergen mentioned in my readings. Some people take it every day. Is this a more successful treatment than the interferon? Is it available in Canada? Thanks.
I believe that most who are treating with infergen are people who have already shown a less then effective result from using one of the pegylated interferons. As a type 1a I treated with Peg-intron and Rebetol(Ribavirin) for 48 weeks and relapsed. The general consensus is that side effects are milder with Pegasys and the copegasys is just another brand of Ribavirin. As a person treating for the first time I believe Pegasys and copeg are a good choice and if I were to treat again those are the drugs I would choose to treat with due to the milder sides. Someone may give you more helpful technical info here. Be patient though as weekends can be slow on the forum. frank
Infergen is a consensus interferon. Unlike the alpha-interferons used in PegIntron and Pegasys, it is not a naturally occuring interferon.
In the U.S., Infergen was approved to treat relapsers or those that did not respond to the alpha-interferon. This was when alpha-interferon monotherapy or combo-therapy (with Ribavirin) with dosing of the interferon three times a week (TIW) was standard treatment.
Some genius doctor (heavy sarcasm) figured out that daily dosing of interferon, in this case Infergen, produced better results than TIW dosing. So, prior to the pegylated interferons PegIntron, Pegasys, daily Infergen + Ribavirin was the best show in town. Daily Infergen + Riba is still a good option for retreatment.
Once upon a time, I read that a pegylated version of Infergen was being developed. I've quit constant active research, so I don't know where it is in development/testing.
I hope this helps. -Michael
In the U.S., Infergen was approved to treat relapsers or those that did not respond to the alpha-interferon. This was when alpha-interferon monotherapy or combo-therapy (with Ribavirin) with dosing of the interferon three times a week (TIW) was standard treatment.
Some genius doctor (heavy sarcasm) figured out that daily dosing of interferon, in this case Infergen, produced better results than TIW dosing. So, prior to the pegylated interferons PegIntron, Pegasys, daily Infergen + Ribavirin was the best show in town. Daily Infergen + Riba is still a good option for retreatment.
Once upon a time, I read that a pegylated version of Infergen was being developed. I've quit constant active research, so I don't know where it is in development/testing.
I hope this helps. -Michael
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