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Looks like I'm being invited to the dance - Phase 2 Study of Telaprevir (VX-950), Pegasys and Copegus in Hepatitis C
Yesterday I heard from my doctor that they are trying to enroll me in the Phase 2 VX-950 trial, which is great news and something I've been asking for.
My dilema is that I'm absolutely swamped with commitments from work, church and family...more than usual. I'd like to hear from the VX-950 people here on the board just how crappy they feel and if they are working effectively. I own a business with a high profile role that require much travel.
On my last tx with Peg-Intron and RBV I felt pretty worn down after 8 months. I'm certain that I could take 3-6 months of this but would only do a year again if my health forced it.
My background is 49 year old male, contracted HCV about 25 years ago; geno 1b; Stage 1/Grade 0; started tx with 3M VL; no EVR but did get a 4log drop at week 2; eventually dropped to 9,600 but started to rise around month 8; game over. Other that HCV and some newly found arthritis I'm in great shape and run 15-20 miles per week.
So, I really have a few questions that you guys could help me with:
1.) VX-950 people...how crappy do you feel?
2.) Who's done both Pegasys and Peg-Intron. Which made you feel crappier?
3.) Given my stats, would you jump on the wagon now or wait to see if they can dial this tx down to 3 months, which I could do standing on my head.
Thanks,
Mike
My dilema is that I'm absolutely swamped with commitments from work, church and family...more than usual. I'd like to hear from the VX-950 people here on the board just how crappy they feel and if they are working effectively. I own a business with a high profile role that require much travel.
On my last tx with Peg-Intron and RBV I felt pretty worn down after 8 months. I'm certain that I could take 3-6 months of this but would only do a year again if my health forced it.
My background is 49 year old male, contracted HCV about 25 years ago; geno 1b; Stage 1/Grade 0; started tx with 3M VL; no EVR but did get a 4log drop at week 2; eventually dropped to 9,600 but started to rise around month 8; game over. Other that HCV and some newly found arthritis I'm in great shape and run 15-20 miles per week.
So, I really have a few questions that you guys could help me with:
1.) VX-950 people...how crappy do you feel?
2.) Who's done both Pegasys and Peg-Intron. Which made you feel crappier?
3.) Given my stats, would you jump on the wagon now or wait to see if they can dial this tx down to 3 months, which I could do standing on my head.
Thanks,
Mike
I agree with jim, if I had to choose I would wait awhile.I like to see the results first before putting yourself through it all. best of luck :)shelly
Why not wait at least until the trials for non-responders produce some results? Why be a guinea pig when you're only stage 1? At least consider waiting out this year to see the results of the current trials for treatment naives. Personally, if I was a stage 1, I'd probably wait for a non-interferon therapy to come along although that may be awhile. I might change my mind, however, if the 12 week Vertex ARM produced decent odds for success. Hopefully, Fibroscan will be more readily available soon which should make "watch and wait" even more viable.
Be well,
-- Jim
Be well,
-- Jim
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