LadyLauri did the doctor ever say what was causing the bruising?
merryBe quit punching your !@#$% liver !
Week 5 trough week 16 had me just about 100% bedridden, hardly able to make it to the bathroom. It was the ribavirin induced anemia, the fall in hemoglobin that hit me hard. From week 17 on it has been much better, my body has gotten adjusted to the low hemoglobin level. I went from baseline 15.2 to between 10 and 11.
I figured this was just to be expected from these heavy drugs. You are a geno 2 and RVR, so hopefully you can pull it off with lower doses. As a geno 1 and slow responder, I would never have dared to.
no expert, but I think when I caught a bug in November that's what kicked my cronic hep (at that time undiagnosed) into acute hep. lie in bed, moan, punch your liver every 3 seconds to break the pain signal, and do it again.repeatly for 18 hr, sleep 14, and do it all again.
I really think something triggered the acute stage either virally or because I ended a growth hormone trial (where my body was getting some help) and had to go without that helper hormone.
in any case I got an identical repeat of the symptoms when first going on tx, especially week 2 and 3 and I think this is because the immune system just kicked into an even higher gear.
either way, when the body is intently fighting or trying to you are going to feel fagged out.
the thing I'd be concerned about here is whether when you say no rescue drugs in these trial what do you mean???
It's really important to get rest for instance, and into 3rd and 4th stage sleep to do any serious tissue repair....so are you still allowed to get something for sleep from them or your GP.
without this I was waking up in pain and sweats 30-60 times a night...so very important to protect that function. this one thing can immensely aide how many new blood cells and platelets your body will make, almost all cell replacement occurs in deep sleep. also I wrote a thread called Know This, you may find helpful...although it's a fight to get on this.
hope something helps you.
Your bloods look great, especially your ALT. The only thing that I can see that is low is your haematocrit which is only slightly low anyway.
From http://www.medterms.com/script/main/art.asp?articlekey=4561
Definition of Neutrophil (Neuts)
Neutrophil: A type of white blood cell, specifically a form of granulocyte, filled with neutrally-staining granules, tiny sacs of enzymes that help the cell to kill and digest microorganisms it has engulfed by phagocytosis. The mature neutrophil has a segmented nucleus (it is called a seg or poly) while the immature neutrophil has band-shape nucleus (it is called a band). The neutrophil has a lifespan of about 3 days.
Neutrophilia, an increased proportion of neutrophils in the blood, is a common finding with acute bacterial infections.
Neutropenia, a decreased proportion of neutrophils, may be seen with viral infections and after radiotherapy and chemotherapy. Neutropenia lowers the immunologic barrier to bacterial and fungal infection.
From http://www.mydr.com.au/default.asp?article=3011
Packed cell volume (PCV) or haematocrit (Hct) is a measure of the percentage of red blood cells to the total blood volume.
A low haematocrit may indicate anemia, blood loss, bone marrow failure, leukaemia, multiple myeloma, nutritional deficiency, over-hydration or rheumatoid arthritis.
A high haematocrit may indicate dehydration (for example, due to burns or diarrhoea), eclampsia (a serious condition that can occur during pregnancy) or polycythaemia vera.
The normal haematocrit range for adult males is 40-50 per cent, and 36-46 per cent for adult females
CS
sorry to hear your bedriddin during tx. i hope that turns around for you soon. i am glad you are still fighting to continue on tx. i am sure i speak for all of us ; we are pulling for you. the test results you have listed are better understood if you know the high low factors of each result and were you started at would really help you if you new those results. i have read in this group recently that readings such as the ones you have listed will bounce around during treatment and that other drugs are available to help your body continue the tx. as i said at the beginning of your tx knowledge is powerful and just a little bit of it can go a long way. i would suggest that doing a search under blood test alt test results neut test results etc will help you better understand what they mean. if the study you are under does not provide enough answers for you i would also seek a second opinion as soon as possible so that you have ammo to work with. it looks like we are going back to school "GRASSHOPPER"
Hang in there!!! : o )