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1253246 tn?1332073310

Milk Thistle???

Very Interesting I must say!!!


New evidence implies that milk thistle interrupts the Hepatitis C virus' reproduction and proliferation cycles.

by Nicole Cutler, L.Ac.

For centuries, the extract from the milk thistle plant has been used to improve liver function. This practice is widely recognized - especially by the millions of people living with chronic Hepatitis C - a viral infection that can cause progressive damage to the liver. Hundreds of studies have provided evidence that silymarin, milk thistle's extract, is a potent liver cell protector. However, there have also been an abundance of conflicting reports regarding milk thistle's ability to directly affect the Hepatitis C virus. Providing even more reason for those with Hepatitis C to take milk thistle, a new study tips the scales of doubt by showing that silymarin exerts multiple effects against the lifecycle of the Hepatitis C virus.

Two previous studies that have indicated silymarin's usefulness against Hepatitis C include:

· The February 2008 issue of Hepatology looked at milk thistle use among 1,145 participants in the HALT-C study, sponsored by the National Institute of Diabetes and Digestive and Kidney Disease. Although milk thistle users in this study showed similar liver enzyme levels and Hepatitis C viral loads to non-users, those taking milk thistle showed fewer liver-related symptoms and an improved quality of life.

· The March 2010 issue of Gastroenterology published a French study where researchers evaluated a commercially available intravenous preparation of silibinin - the most active component of silymarin - in those with the Hepatitis C virus. The researchers agreed that silibinin inhibited Hepatitis C polymerase function - a result comparable to what the STAT-C (specifically targeted antiviral therapy for Hepatitis C) drugs can do - without their accompanying hazards.

The new study that further identifies milk thistle as an anti-Hepatitis C substance examined the antiviral properties and mechanisms of silymarin on cultured (grown in a lab) human liver cells infected with the virus. The study, funded in part by the National Center for Complementary and Alternative Medicine (NCCAM), was published in the June 2010 edition of the journal, Hepatology.

After growing human liver cells and infecting them with the Hepatitis C virus, the cells were exposed to either standard Hepatitis C drug treatment or a diluted dose of silymarin. The researchers then found the following:

· Silymarin prevented the entry and fusion of the Hepatitis C virus into the target liver cells.

· Silymarin inhibited the ability of the virus to produce RNA, thus interfering with a portion of the virus' lifecycle.

· When measured against untreated cells, silymarin significantly decreased viral load (although to a lesser degree than treatment with interferon did).

· Silymarin prevented the cell-to-cell spread of the Hepatitis C virus.

Upon carefully taking all of the variables into account, the researchers concluded that silymarin's antiviral action appears to include blocking the entry and transmission of the Hepatitis C virus, possibly by targeting the host cell.

Experts agree that more well-structured trials are needed to understand, quantify and verify silymarin's effectiveness against the Hepatitis C virus. More ammunition is required to break down the wall of doubt surrounding this herb's contribution to the Hepatitis C community. In the meantime, there is sufficient evidence confirming silymarin's ability to protect liver cells and improve liver function - two properties that everyone with Hepatitis C could benefit from.
28 Responses
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315996 tn?1429054229
I saw one study that said the Walmart brand, Spring Valley, had the most honest contents. This was for knee joing stuff, you know, those two items, can't remember the names.
Helpful - 0
179856 tn?1333547362
Doc told me NOT to take it ON treatment so check that out.

Helpful - 0
1253246 tn?1332073310
Puritans Pride is the maker .Google it and youll find they make every vitamin know to man!!!
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Avatar universal
Yes I agree. I do buy the brads at wal-mart but they contain little of silymarin.I take 4000-6000 mg a day just to get the desired dose of silymarin…
Helpful - 0
Avatar universal
Thanks. I just bought some over the internet. Was buying a more expensive brand and taking 3 times a day . It was doing anything for me, maybe the brand or not enough dosing. I'll try the one from Walmart. Can't beat that pricing.
Helpful - 0
789911 tn?1368636783
Does it matter what brand you take? I have heard people say that some brands like the stuff you can get at walmart or CVS....   is not very goodl    can you just take  silymarin supplement since that is the active ingredient in milk thistle?  I think I have seen both in the health food store.
Helpful - 0
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