Not clear on svr percentages?????

[orleans]

Am I getting this right? What I think I am finding is that around 35% of geno 1 attain svr and 33% of those relaspe after treatment is complete. If this is so, in the spirit of Borat I say "WHAT,  thats not good for me!"

[orleans]

These kind of odds are not looking so good. The cost of treatment is huge in $$$ and life. I haven't had a bx yet but am hoping my liver is in decent enough shape to wait awhile. thanks guys, jm

[jmjm530]

"...For 'difficult-to-cure' patients: genotype 1, high initial viral load > 1 million, overweight > 200 lb
Standard treatment: Pegasys (180 ug/week) + RBV (1,200-1,600 mg/day) for 48 weeks
End of treatment response (UND): around 50%; around 40% of THOSE relapse..."
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I think this means the SVR rate is 30%. (relapse rate is 40% of 50% or 20%/ 50% -20% = 30% SVR)

[Valtod]

For 'difficult-to-cure' patients: genotype 1, high initial viral load > 1 million, overweight > 200 lb
Standard treatment: Pegasys (180 ug/week) + RBV (1,200-1,600 mg/day) for 48 weeks
End of treatment response (UND): around 50%; around 40% of THOSE relapse

See http://www.natap.org/2006/AASLD/AASLD_43.htm

<IMG SRC="http://www.natap.org/2006/images/110706/figure3ViroRes-4.gif">

[sfbaygirl]

Cool chart! But does that include only those that made it 48 weeks, or does that not include them?

Goof; Love those stats, but that would mean only 10% relapse? It would seem to be more. I know we talked about improved chances of SVR as each UND happens...at 12, 24, 36 weeks. It would be curious if the data about not dropping out, VL breakthrough, non responder, etc were not put into the equation.

[cuteus]

so now you got the svr rates for the hard to cure and the easy to cure.

[cuteus]

orleans, 58% hard to cure patients get SVR, I think those are excellent odds.