Effects of Food on Oral Absorption
The systemic exposure (AUC) to telaprevir was increased by 237% when telaprevir was administered with a standard fat meal (containing 533 kcal and 21 g fat) compared to when telaprevir was administered under fasting conditions. In addition, the type of meal significantly affects exposure to telaprevir. Relative to fasting, when telaprevir was administered with a low-fat meal (249 kcal, 3.6 g fat) and a high-fat meal (928 kcal, 56 g fat), the systemic exposure (AUC) to telaprevir was increased by approximately 117% and 330%, respectively. Doses of INCIVEK were administered within 30 minutes of completing a meal or snack containing approximately 20 grams of fat in the Phase 3 trials. Therefore, INCIVEK should always be taken with food (not low fat).
It is important to eat the required fat grams for proper absorbtion
after I have stopped incevik it was about five weeks until I felt better by better I mean about 70% of myself. I am still taking Pega interferon and Riba for another thirty one weeks. I still have brain mush but I know that is from the interferon ... You two hang in there !!!!
I am going into my 4th week of tx, what happens if you don't get all the fat grams you need with med? I have found that the wet wipes and then using aquaphor or vaseline keeps the burning and itching of the rectum at bay.
My husband did the treatment with the three cocktails for 4 weeks. His platlet count fell down around 28000 and he was admited into the hospital for treatment and given platlets and patasiom, that was on a Monday and he was released on Tuesday. He went and had blood work done on Friday and he platlets were droping again. We went to his doctor the following Thursday and he told him that he could not go through the treatment and stopped everything. My husband is still so sick that he can not hold his head up. How long, are does anyone know, does the side effects last after stopping the treatments?
While the tx was horrible, I am now 2 months post tx and I have to say I feel better than I have in many many years
After I treated the first time I felt horrible, never felt like myself again, until now. Now I know it was the virus continuing to cause damage that was making me so sick. I could not have worked during the first 12 weeks of Invicek
It amazes me what I am reading here.