Hi,
My first treatment in 2000 was the old,non-peg combo.
Biochemical response only.
Treat.2 in 2001 Roche peg.+RBV 1000mg,RNA down to 6500.
Ceased owing to g.i problems.
Treat.3 2002,Same regime RNA down to 3000 at 12 weeks,ceased at week 18 due to anemia.hg 7.5
Treat 4,in progress.
My expectation is that I'll test undectable at wk.24,but that anemia will end treatment pre-maturely.
If so I will re-treat with Viradimine replacing RBV.
I also have the option of low dose IF mono maintainance therapy.
I changed doctors this year.Both are top dogs,Professors of Medicine specialing in viral Hepatitis.
My Doc. said he would like to use Fibroscan,but it cots
As a cirrhotic 3a, I was advised to treat for 48 weeks. They report high relapses with less treatment. At 48 weeks they claim 60% probability of cure. I'm a 47 yo male, with reasonable body mass index (5'9" @ 163 lbs naked, dry & empty, lol). I think males are harder to treat.
I was told red meat was OK in moderation, and coffee was a 'non-issue'. Just to maintain a common sense healthy diet. As Jim says, check with your doc, your mileage may vary.
Marijuna (medical of course ;)) was suggested to me during tx to help nausea and weight loss. The drug does not agree with me so I declined. I personally see no problem with red meat or coffee but as I mentioned before run EVERYTHING by your doctor or Nurse Practioner. If they're going to treat you effectively, you must keep them informed of what you're taking. Your weight sounds great and this is going to help you with treatment.
Not to second guess the esteemed Cleaveland Clinc (OK I will ;) ) but have you discussed treatment length beyond the 24 weeks because of your cirrhosis? Sometimes people treat a little longer with cirrhosis, especially if they respond slowly -- although in your case your other medical concerns may be an issue.
Ask your doctor if he's planning on testing you for viral load at week 4. That tells your treatment team an awful lot regarding how the drugs are knocking down the virus.
BTW the 70% figure sounds very realistic even with 24 weeks.
-- Jim
P.S. I am having that stomach scope next month and also I have polycystic kidneys to deal with too!
Welcome from the other side of the pond :)
Your profile is similar to mine. Curious what you treated with the first time (Peg Intron, Pegasys, Riba, dose, etc.) and what specifically you mean by "partial response" in terms of when you tested viral response and results.
I was also a sofa case for the first 12 weeks although my hemoglobin never dropped that low. Things are better now at week 28 but not a lot. Just gotta keep your eye on the prize.
Hope you have better luck this time around. A few days ago I spoke to a leading researcher and he said that in five years he thinks he will be able to cure just about anyone with the newer drugs currently in trial. So let's hope we both clear this time, but if not, my plan now is probably to wait for the newer drugs.
BTW do you have the Fibroscan test in England. We have three or four test units in the U.S. in trial for FDA approval. It's a very exciting development for dx, tx and research.
-- Jim
Hi again,
I am genotype 3a and V/L of 1.5 mill. I am 5'9" and 122#. My doc said about 70% chance of clearing (i guess because of the cirrhosis). I had active TB about 14 years ago which is a concern and also had 4 reactivations of Toxoplasmosis in my eyes, which also is a concern. Its a wait and see game I guess with these issues. Is coffee and red meat ok to eat? And is mary jane something that can really help side affects of tx? Im all for herbal supplements....lol!