Telaprevir Launch Could Be Delayed to 2012

[Bill1028]

This sucks!

http://money.cnn.com/news/newsfeeds/articles/apwire/da3e9a9e4c40232cc4c40734b0762a6c.htm

[Bill200]

Hey guys just wondering what genotype y'all are?  I'm 1b and have failed to clear in three treatments.  So when you guys say you cleared I'm wondering about your history.  I'd like to do telaprevir but they so far won't let previous non-responders join yet.

[FullOfHope77]

I too had a lot of issues in ARM B of the study and couldn't/didn't do the last 5 days of 24 weeks of Telaprevir just pschological I think. I had the rashes galor but after stopping and treating with creams the rashes slowly disappeared. i'm only in week 31 now and do have the 'feelings' of anemia that I haven't had before during SOC and it's requireing me to work from home due to feeling like I'm dizzy and shouldn't drive but that's a confidence thing and I have someone who can drive me when I need to go somewhere.

So, I have all the situations covered and feel that if this works like it seems it will (I was RVR at week 3) probably week 2 but after 2 full treatments I was UND; then I feel it's ready and worth making it available to the masses and feel like thousands if not millions are getting ripped off all for the wrong reasons.

I thought about investing in the stock while so cheap but the PR is so misleading I'm afraid it will go down and have to wait it out even longer while it finally works itself out of the anaylst hail. If I don't invest and it goes up then I will really feel stupid but most importantly this is not about the money it's about the people that can benefit sadly that seems to be forgotten during these times.

Scotty

[lab-rat]

Thanks willows  I've also considered that if I really wanted to, I could drop out of the study at 24 weeks and extend SOC treatment on my own (not sure if I could get any insurance to cover that).  But I guess I'll cross that bridge when (or if) I get to it!

[scratchinghead]

thanks, for whatever reasons.

[willows]

All the concern about chance of mutation is so murky to me....if I had a chance to try telaprevir for 12+12, I would go for it too.  Good luck to you.  SOC for 72 weeks is not covered by protocols anywhere...plus, so many folks have had good luck with telaprevir at just 12 weeks.  I'm not sure we will ever see dosing for telaprevir for any longer than 12 weeks anyway.  As far as extending SOC into 72 weeks beyond the 12 weeks of telaprevir...why can't a person do that now?  

Again, good luck to you...we'll be here wishing the best for you.

Willow

[lab-rat]

As a relapser of prove 1 (SOC) - your posts regarding the chances of relapsers re-treating w/ vx caught my eye.  I'm eligible to join the rollover trial, (and get the real thing this time) however my study Dr. did not recommend it since it's only a 24 week trial (12 wks of telaprevir w/ 24 wks inf + riba).  His opinion was that I should re-treat (SOC) for 72 weeks and was concerned about chance of mutation.  Or that I wait for a trial of longer duration.

I decided to join the rollover trial anyhow (hopefully not a big mistake) - and that doctor thought I was making the right choice.  Only time will tell..but she did say that she would do it if she were in my shoes (after I decided to join)...and also that most trials are just not available to relapsers.  The chances of getting access to a new drug is greater for someone who is treatment naive.