Thanks for commenting. This is really ridiculous and as said, not acceptable. Either there is an explanation or there isn't, and they haven't come up with one that makes sense.
Does your study use Quintile Laboratories? I'm just curious if each study site has to use the same lab or testing protocols.
You have me wondering also...seeing as we have the same trial pharma company in common. With that being said....if you tested again in a month or so and it was still <25...then I guess it would be about the same as UND as the virus hasn't replicated. But....I am not a doctor. Only wishing you...me...and the rest of us SVR.
Yes, this is not just something I can accept without further testing, but I don't understand why the trial won't retest and are good with calling it UND and an SVR. This is truly unacceptable information.
I'm going to have to pursue another test on my own since they don't feel the need to retest. I don't know how they can validate this as a SVR in their published results of the study. It sure makes me wonder how valid their stats on SVRs have been in reports from past years.
I would definetely get retested. From what I have learned at my clinic...<25 means the VL load is somewhere between 1-25, but the machine can't quantify the number...where no viral load is 'target not detected". I was <25 week 1 and 2 of my 12 week study (gilead) and "target not detected weeks 4,8 and 12. I had these same questions before I went UND. I hope and pray you retest UND. Good Luck
What do you think about the lab's explanation that "<25" means the same thing as "undetected" or "target not detected" and calling it another SVR in their study? As a subject in a trial I don't know if I can directly contact the lab myself, but I am going to find out.
Thanks for the reply. It seems odd that a lab that uses both terms, "target not detected" and "<25" would say they are one and the same, then why have two terms for UND? Very disturbing to get this result at wk 24 post tx.
It's ridiculous that there is not a better explanation from the lab.