Aa
Viral Load
My Husbands Type is 1 and his starting viral load about 5.5million. Doctor just said "it shows that the virus level has dropped to about 1% of its prior level which is encouraging. .. Can anyone shed more light then just encouraging for me please. I dont know what to expect regarding the speed at which it drops.. Seems 99% in 4 weeks is very good is that correct?
“Log drop” refers to another way of looking at viral load through the use of logarithms.
An example:
Baseline viral load of 1,500,000
150,000 = 1 log reduction (-90%)
15,000 = 2 log reduction (-99%)
1,500 = 3 log reduction (-99.9%)
150 = 4 log reduction (-99.99%)
The PCR count is equivalent to viral load; the PCR test is used to calculate viral load.
No, unfortunately one must be undetectable for virus at 4 weeks in addition to having started therapy with a low viral load (<400,000 IU/mL) to qualify for abbreviated therapy. Additionally, there cannot be HIV or cirrhosis present either.
Good luck, and welcome--
--Bill
An example:
Baseline viral load of 1,500,000
150,000 = 1 log reduction (-90%)
15,000 = 2 log reduction (-99%)
1,500 = 3 log reduction (-99.9%)
150 = 4 log reduction (-99.99%)
The PCR count is equivalent to viral load; the PCR test is used to calculate viral load.
No, unfortunately one must be undetectable for virus at 4 weeks in addition to having started therapy with a low viral load (<400,000 IU/mL) to qualify for abbreviated therapy. Additionally, there cannot be HIV or cirrhosis present either.
Good luck, and welcome--
--Bill
To be considered RVR (rapid virological response) you must be UND (undetectable by PCR) at 4 wks.
You said your husband's starting viral load was at 5.5 million. To obtain that number they did an HCV RNA by PCR. In order for your doctor to state he has cleared 99 percent of the virus another PCR was done.
Log drops are calculated by subtracting the zeros off the end of the initial viral load.
For instance 5,500,000 with a two log drop would be 55,000. A three log drop would be 5,500 and a four log drop would be 550.
Trinity
You said your husband's starting viral load was at 5.5 million. To obtain that number they did an HCV RNA by PCR. In order for your doctor to state he has cleared 99 percent of the virus another PCR was done.
Log drops are calculated by subtracting the zeros off the end of the initial viral load.
For instance 5,500,000 with a two log drop would be 55,000. A three log drop would be 5,500 and a four log drop would be 550.
Trinity
Let me start by saying I am so glad you are all here blogging because the doctor makes us feel like a number, if you know what I mean.
What is all this log drop people talk about?
What is the PCR count?
At 99% in 4 weeks that is still not considered a rapid responder who could cut the treatment short?
What is all this log drop people talk about?
What is the PCR count?
At 99% in 4 weeks that is still not considered a rapid responder who could cut the treatment short?
the remaining 1% from 5.5 mil is about a log 2 drop in viral load.
Log 2 drop at end of wk 12- is absolute minimum requirement to continue treatment. VL should be undetectable at the end of wk 12 for a possible svr outcome at end of treatment and beyond..
Now since he has reached the log 2 drop at week 4, there are 8 more weeks on his side to improve the VL and become undetected at end of week 12, which is an important milestone in making treatment decisions.
So it is encouraging to know that he is responsive to treatment and it is a good earlier number indicating that the treatment is on track.
Log 2 drop at end of wk 12- is absolute minimum requirement to continue treatment. VL should be undetectable at the end of wk 12 for a possible svr outcome at end of treatment and beyond..
Now since he has reached the log 2 drop at week 4, there are 8 more weeks on his side to improve the VL and become undetected at end of week 12, which is an important milestone in making treatment decisions.
So it is encouraging to know that he is responsive to treatment and it is a good earlier number indicating that the treatment is on track.
Is that 5.5 million to about 50,000?
Thats about a 2 log drop, which is what they are looking for in the first 12 weeks
When I treated, I thought my 96 per cent drop was good, but it really is just so so.
Thats about a 2 log drop, which is what they are looking for in the first 12 weeks
When I treated, I thought my 96 per cent drop was good, but it really is just so so.
Have an Answer?
You are reading content posted in the Hepatitis C Community
Learn about this treatable virus.
Getting tested for this viral infection.
3 key steps to getting on treatment.
4 steps to getting on therapy.
What you need to know about Hep C drugs.
How the drugs might affect you.
These tips may up your chances of a cure.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
