Aa
When do the side effects STOP?
So, i have only 5 more incevik doses, tomorrow is my last day thank you GOD, i have had every side effect thought i had escaped the rash/itching but the last few weeks have been pretty bad i have red welts that wont heal all over my lower legs, bumps on my thighs and arms, itching EVERYWHERE including crotch itch and butt itch argggg and who can forget the constantly recurring diarrhea... lovely... so, my last dose is tomorrow night, 10pm, when do the side effects STOP????????????
i am attributing every single one of my side effects to the Incivek and once i am done (TOMORROW !!!!) i will be side effect free... lol...fingers crossed... i had the diarreah one hour into my first dose of Incivek and i have been on peg before didnt have any itching or diarrea then ...first time on the riba however...
http://www.medhelp.org/posts/Hepatitis-C/Radioactive-Incivek------What-/show/1616159?controller=posts&action=show&id=#
This will answer your question.
This will answer your question.
Side effects have always been part of this treatment. Although some of your side effects will be gone once you are off the INC, the ones from the interferon and ribavirin live on, and those have always been major in their own.
The diarreah may be partially caused by the interferon, and you will be able to sort of which rashes and itching are from the ribavirin soon. Anal itching, associated with the diarreah may also continue. Headaches, muscle aches, anemia, neutropenia, -- these are all associated with SOC.
I too have welts and what i call "hot spots" which itch like all get out -- and I am on VIC. At least some of your sides will ease and it may seem like a cake walk after INC. I hope so.
frijole
The diarreah may be partially caused by the interferon, and you will be able to sort of which rashes and itching are from the ribavirin soon. Anal itching, associated with the diarreah may also continue. Headaches, muscle aches, anemia, neutropenia, -- these are all associated with SOC.
I too have welts and what i call "hot spots" which itch like all get out -- and I am on VIC. At least some of your sides will ease and it may seem like a cake walk after INC. I hope so.
frijole
what does it mean by 'radioactivity' what the heck i didnt know i was being radiated here... wtf
ahh yes good i cant wait... lol... i broke down and took an allergy pill this a.m. only the second one since treatment but i couldnt stand it anymore hate taking them becuz they make me sleepy and even more dehydrated than i already am...
Elimination
Following administration of a single oral dose of 750 mg 14C-telaprevir in healthy subjects, 90% of total radioactivity was recovered in feces, urine and
expired air within 96 hours post-dose. The median recovery of the administered radioactive dose was approximately 82% in the feces, 9% in exhaled air and
1% in urine. The contribution of unchanged 14C-telaprevir and the R-diastereomer of telaprevir towards total radioactivity recovered in feces was 31.9% and
18.8%, respectively. After oral administration, the apparent total clearance (Cl/F) was estimated to be 32.4 L/h with an inter-individual variability of 27.2%.
The mean elimination half-life after single-dose oral administration of telaprevir 750 mg typically ranged from about 4.0 to 4.7 hours. At steady state, the
effective half-life is about 9 to 11 hours.
http://pi.vrtx.com/files/uspi_telaprevir.pdf
Most of the directly incivek related sx were gone for me within a week but took about 10 days before I really started to feel any better
Following administration of a single oral dose of 750 mg 14C-telaprevir in healthy subjects, 90% of total radioactivity was recovered in feces, urine and
expired air within 96 hours post-dose. The median recovery of the administered radioactive dose was approximately 82% in the feces, 9% in exhaled air and
1% in urine. The contribution of unchanged 14C-telaprevir and the R-diastereomer of telaprevir towards total radioactivity recovered in feces was 31.9% and
18.8%, respectively. After oral administration, the apparent total clearance (Cl/F) was estimated to be 32.4 L/h with an inter-individual variability of 27.2%.
The mean elimination half-life after single-dose oral administration of telaprevir 750 mg typically ranged from about 4.0 to 4.7 hours. At steady state, the
effective half-life is about 9 to 11 hours.
http://pi.vrtx.com/files/uspi_telaprevir.pdf
Most of the directly incivek related sx were gone for me within a week but took about 10 days before I really started to feel any better
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