Aa
fishdics consults-interesting
OK, everyone in the area of Albuquerque, Dr. Arora is the real mccoy. I put 11 years of labwork into a spreadsheet, my list of questions, and this is the skinny. Just to update those that don't remember, baseline 2,890,000 12 week was 38,700. His resident said "thats close enough", and I was thinking HUH UH< I have read the literature... Dr. came in with two students, and said. You failed to achieve a 2 log drop. If you continue the current course, you have a 5% or less chance of SVR. However, it may be that you are not a true nonresponder, because your hemoglobin has remained virtually unchanged, which tells me you are one of less than 5% of patients that hypermetabolize ribavarin. ( he has conducted 17 clinical trials with ribavarin) Essentially, you are on monotherapy. Options: increase ribavarin, 6 weeks at 1400, then up to 1600 for another 6 weeks, redo the PCR. If you are undetectible at the 12 week, you have a 65% chance of SVR. If you fail to hit undetectible, then stop the treatment. If I am undetecitible, my 48 weeks starts today. If I stop, and start again in 6 months, you start out with the same odds as this time (I wondered about that). He also said that he has a VX-950 trial coming up for....... nonresponders. You have to have failed to achieve a 2 log drop, and failed to hit undetectible at 24 weeks. Starts in 6 months or a year. So trip was well worth it. Cops came and hauled the crazy uncle off while I was gone, man, I'm a making progress. Thanks for all your well wishes, I could feel the vibes...
You know me cat, I wake up in the middle of the nite , everynite . Riba really speeds my a-- up. Straight jacket time dude, hmg is 10.4 , 5 pts down from base. They put me on paxil thursday , the men in the white coats said it would settle the dyce down. Shot 13 is chickin wiggin me right now too. Got arond 7 hours a snooze , so I'm all ribbaed up, guy , but it feels like I built some blood by restin. Me alt is 28 and the ast is 30 , ggt came down ta 112 from 180 sumthin. Riba diba daba dooooooooo!!!!!!!!!!
Well, I'm up too. It's 4AM and I'm up, only 3hrs sleep again. Wonder if it's the new blood.
Dyce you have a point, that's what I was trying to figure out. From other posts those that had their HGB drop from base line seem to have the best results because the more red blood cells it's killing the more HCV bugs are being killed, so why would it be a different approach for fishdoc or the 5% or less of the population with HCV who HGB doesn't drop from baseline.
BEAGLE
Dyce you have a point, that's what I was trying to figure out. From other posts those that had their HGB drop from base line seem to have the best results because the more red blood cells it's killing the more HCV bugs are being killed, so why would it be a different approach for fishdoc or the 5% or less of the population with HCV who HGB doesn't drop from baseline.
BEAGLE
As you all know, I'm on the 8 Riba's a day. I haven't been able to tell a whole lot of difference in how I feel compared to 4 a day. As far as my hemoglobin/RBC, my doctor just put me on Procrit and has been following my labs closely. So, that hasn't been an issue either.
Susan
Susan
he said six months or a year, so perfect timing to give me another 3 months pass or fail.....of course, now I'm wondering...if 6 of the damm things weren't helping, why would adding one more help... or two more..my mind is my worst enemy at times....how you doing? Yeah, had a big stink at home-Uncle saw our suitcase, Bill was taking me to the appt. and we were going to stop ata motel up in the mountains, and just spend some time this morning hanging out in the cool hills. He was wanting us to take him to relatives in phoenix, so after we left, he had a huge fit at my mom....who is 78... a true bully. He took off walking down the road, cops brought him home, and said he was dangerous, and he is sitting in a mental care facility this morning, which is where he should have been right from the start....
You got your hands full with with your uncle, at least when you get home he won't be there.
I agree with you, if 6 didn't work why would adding just 1 more at this point make a differents. I was always lead to believe that the first 3 months of treating was the most important time in the treatment stage. Like dyce pointed out that low HGB durning tx shows that the virus is being killed at least that's what some studies have shown. I got to say I'm confused,but these days it doesn't take much to confuse me.
BEAGLE
I agree with you, if 6 didn't work why would adding just 1 more at this point make a differents. I was always lead to believe that the first 3 months of treating was the most important time in the treatment stage. Like dyce pointed out that low HGB durning tx shows that the virus is being killed at least that's what some studies have shown. I got to say I'm confused,but these days it doesn't take much to confuse me.
BEAGLE
Why are you extending? Is there a reason or you just want to make sure you are SVR? I too finish on the 5th of Aug......AHHHHHH you extended so we could finish tx together! What a pal! 10 more shots after tonight! WOOHOO!
Fisheress
Fisheress
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