Hi and Welcome. The side effects can be overwhelming but truly it is how well they are managed. You may not experience anal irritation. These meds hit everyone differently.
★ Dermatologic side effects have included rash (56%) and pruritus (47%).
Here is a link on the (possible) rash:
http://www.medhelp.org/posts/Hepatitis-C/Hepatitis-C-rash-length/show/1815969
★ Gastrointestinal side effects have included nausea (39%), diarrhea (26%), vomiting (13%), hemorrhoids (12%), anorectal discomfort (11%), anal pruritus (6%), and rectal burning. Anorectal side effects have been reported in 29% of patients.
Here is a link on this:
http://www.medhelp.org/posts/Hepatitis-C/Incivek-and-Anal-Dragon-Fire/show/1737083
For the Nausea:
http://www.medhelp.org/posts/Hepatitis-C/Zofran/show/1770820
Since space is limited to how much info can go in one post here are a few threads that might help you prepare and know what to ask your nurse about. Plus others will post and have suggestions.
If others do not address ☆the fat requirement☆ anaemia, or overall body aches (and the sides of Interferon) be sure to ask your nurse.
Be sure to ask who you call when you have questions. Get a phone #.
Best of luck and be sure to keep in touch as you d t have to go through this alone :)