part tw0

[Deb_c430]

Iron Evaluation
During EPOGEN® therapy, absolute or functional iron deficiency may develop. Functional iron deficiency, with normal ferritin levels but low transferrin saturation, is presumably due to the inability to mobilize iron stores rapidly enough to support increased erythropoiesis. Transferrin saturation should be at least 20% and ferritin should be at least 100 ng/mL.
Prior to and during EPOGEN® therapy, the patient’s iron status, including transferrin saturation (serum iron divided by iron binding capacity) and serum ferritin, should be evaluated. Virtually all patients will eventually require supplemental iron to increase or maintain transferrin saturation to levels which will adequately support erythropoiesis stimulated by EPOGEN®. All surgery patients being treated with EPOGEN® should receive adequate iron supplementation throughout the course of therapy in order to support erythropoiesis and avoid depletion of iron stores

https://www.clevelandclinic.org/myeloma/Procrit_phaseII_less_frequent.htm

"...Must have transferrin saturation of at least 20% and serum ferritin of at least 50 ng/mL If transferrin saturation is < 20% or serum ferritin < 50 ng/mL, the investigator may utilize bone marrow evaluation results or clinical judgment to determine if iron stores are adequate . If inadequate, the patient will be supplemented with iron..."

thank you again to all who helped me get here

[FlGuy]

I was lucky that I achieved hgb equilibrium easily. But in the world of HCV 'lucky' is a relative term and sometimes disassociated with reality. One person might feel 'lucky' treating twice and and another might feel 'lucky' for treating once in a fifty six week experience from hell.

[jmjm530]

FL: I was very happy using Aranesp which is longer lasting than procrit and seemed an easy task for hematologist to regulate to keep hgb in the desired range, the desired range being between 11 and 12
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Not to be a horse's arse, but I would think the Procrit brand of Epo would be easier to tweak since dosage can be changed weekly. I will say this about Aranesp though -- if the Aranesp reps I saw at my doc's office are at all representative, one look should be good for a least a one point rise in hemoglobin.

[Deb_c430]

flguy, no worries I thought it was funny!  because as soon as i did it,  I thought oh geesh! dingbat I am, naw no worries,   I have no problem laughing at myself!  

I just really think the riba and procrit/iron info was good,  Wanted to share, now i have heard that Aransep is a good drug, I will now ask about that lol!

here are the other tests he ordered with this weeks labs

LDL haptoglobulin
Iron studies ferritin Tsat
reticulocyte count

[FlGuy]

Before anyone gets carried away with my posts, I was trying to describe the divorcement of the two parts of the threads. Not at all implying anything with the horse halves anaolgy. But to keep on point a little bit, I was very happy using Aranesp which is longer lasting than procrit and seemed an easy task for hematologist to regulate to keep hgb in the desired range, the desired range being between 11 and 12

[Deb_c430]

That would be me! lol as soon I did  it i thought oh bother!    it is just such good info.

NO politics please!

[FlGuy]

It depends on your point of view as to which one is the horse's arse.

[jmjm530]

Like two guys in a horse costume walking in different directions
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I thought we weren't to have any discussions about the election in this forum.

[FlGuy]

Part 2 could have been conviently placed as the first comment to Part 1.  Now, they will forevermore be separated. Like two guys in a horse costume walking in different directions.