7985 Gilead trail stopping at 12 weeks no riba ION-2

[purplecat]

I was first in the ARM for 12 weeks of Sofosbuvir/5885 NO Riba.  When I started treatment I was told that Gilead modified the study to be 12 weeks with Riba and 24 weeks with and without Riba.  My group was rescheduled for 24 weeks unless response from the 12 week from ION-1 came back over 75% before my 12th week ends.  Well I just got the call my last pill is Wednesday 24April the end of my 12th. I am being put back into 12 week no riba arm.  This means that 75% or greater without riba cleared virus in 12 weeks from ION-1.  I don't know if I should be happy or am disappointed.  I was hoping results weren't back by next week and I would stay for the duration. This drug only has a little GI problem and sometimes headache, that's it.  I know stay positive, I have 75% chance, I was UND the second week when viral load started at over 19 million.  I'm stage 2 not cirrhotic, etc, etc, I have a 75% chance. Good Luck and my god bless everyone no matter what treatment you are doing or going to start.

[mydear52]

I'm doing 8 wks- 79775885/no ribs. This is my first treatment. I think I've had it for about 40 yrs, but found out in 2004, I'm 1b, grade 1, stage 2, VL 2mil.
I pray this works

[mydear52]

I'm in the 8 week trial, 6/11 will be the start of my third week, I'm having some side effects, but none really to complain about. So happy to see this post.

[purplecat]

I was told by my trial nurse that most have cleared by week 4 and a few week 6.  So somewhere between week 3(they do not test) and by week 4 you will also be UND I predict. You are doing great.

[Geshmit]

Hi all

Well it's been 4 weeks; ups and downs with sides.
I am a  bit disappointed as I expected to be UND in week 2, but VL was down to 27. I was 43 the first week down from 5 million and I don't feel as if it's going down fast enough. I'm genotype 1b and doing the 12 week arm of 7985 w riba.

Thanks for your diet tips, purplecat. I'm taking the 7985 with food so I'll try it without to see if it helps gas. Digestive issues better but not perfect - still, it's doable. Had a few bouts of breathlessness, but haemoglobin is ok still.

I'm just concerned that my VL is not moving quickly enough and I only have 12 weeks...

hope you're all doing well

[nobodyone]

How long will you be on this?  I am on the Gilead with RBV  Friday it will be 4 weeks, supposed to do 24 weeks.

[Willy50]

I've been on this for 3.5 weeks. I'm on the riba arm. So far for me no discernible gastro events.

My hemoglobing IS dropping but no food issues I can tell.