Coffee?

[bandman54]

Like many on this site I gave up coffee and caffeine as soon as I was diagnosed.
I have read many places that it was hard on the liver.

But recently I have been finding differing view points re: coffee.

http://www.liversupport.com/wordpress/2006/06/coffees-liver-benefits/

I know this is a pretty old study, but I sure could use a cup of joe!

Does anyone know the real skinny  on coffee/hcv/liver health?

Please site studies if possible as opposed to your experience.

ps - cocksparrow, I left  you a message on nomads.

thank you!
bandman

[bandman54]

thanks all,

I have been looking but I could only find the study I cited.

I am thinking of taking it back up... need the energy!

bandman

[jdwithhcv]

I drank coffee whenever the taste didn't make me gag.  Sometimes it just tasted wrong.  Just my experience, though.  I'm not gonna cite studies because I don't care about studies but you can always do research yourself.

[nygirl7]

I drank coffee and ate chocolate and drank soda (has caffeine too you know) all through treatment and beat geno1A and 1B.

Drink the coffee - my God treatment is hard enough and the studies I read do say it is good for you in fact and can help prevent liver cancer.

[Deb_c430]

I still drink a cup or two a day, I read a french study it helped with fibrous,  But there are so many different views,  I like it and doubt one cup a day or even two is a horrible thing.

My opinion my choice

[meakea]

I know many Hep C patients who still drink their coffee.  I, personally, gave it up.  I would, however, suggest to anyone who does want to enjoy their coffee to at least start buying organic coffee.  There are a lot of unnecessary chemicals in regular coffee (or so I've heard).

[mikesimon]

Ohfuji S, Fukushima W, Tanaka T, Habu D, Tamori A, Sakaguchi H, Takeda T, Kawada N, Seki S, Nishiguchi S, Shiomi S, Hirota Y.

Hepatol Res. 2006 Nov;36(3):201-8. Epub 2006 Aug 17.
    Coffee consumption and reduced risk of hepatocellular carcinoma among patients with chronic type C liver disease: A case-control study.
Department of Public Health, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.

Several studies have reported the role of coffee for hepatocellular carcinoma (HCC). However, no study investigated about the relation of coffee for HCC among individuals with a relevant risk factor, i.e., hepatitis C virus (HCV) infection. Thus, we conducted a hospital-based case-control study to assess an association between coffee and HCC, in which both 73 cases and 253 controls were patients with chronic type C liver disease. To consider potential changes in coffee intake due to progression of liver disease, the effect of coffee was estimated separately before and after first identification of liver disease. Odds ratios (OR) and 95% confidence intervals (CI) for HCC risk were calculated using the conditional logistic regression model. Coffee drinking on a daily basis (>/=1cup/day) revealed lowered ORs as compared with non-drinkers both before first identification of liver disease (OR 0.38; 95% CI: 0.13-1.12; P=0.078) as well as thereafter (OR 0.19; 95% CI: 0.05-0.71; P=0.032). Even after excluding subjects who reported a reduction in the frequency of coffee intake after first identification of liver disease, this negative correlation persisted (OR 0.35; 95% CI: 0.12-1.06; P=0.063). Taken together, coffee may be a protective factor for HCC among those infected with HCV.


Med Hypotheses. 2008 Aug 11. [Epub ahead of print]Click here to read Links
    The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver.
    Tao KS, Wang W, Wang L, Cao DY, Li YQ, Wu SX, Dou KF.

    Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, No. 15 West Chang'le Road, 710032 Xi'an, PR China.

    Epidemiological studies have found an inverse association between coffee consumption and the risk of liver cancer. Animal data support such a chemopreventive effect of coffee. Substantial research has been devoted to the identification of coffee components that may be responsible for these beneficial effects. Based on the current available literature, three major components, i.e. coffee diterpenes cafestol and kahweol (C+K), caffeine and chlorogenic acid contribute to the beneficial effects. These components induce phase II detoxifying and antioxidant enzymes as well as inhibit the expression or decrease the activity of phase I activating enzymes thus prevent carcinogenesis. These components target different stages of a common pathway, Kelch-like ECH-associated protein 1 (Keap1) - NF-E2-related factor-2 (Nrf2) - antioxidant-responsive-element (ARE) signal pathway thus alter the ARE-dependent expression of genes needed in the anti-tumorigenic effects.