Orlistat has been a big hit for both Glaxo and Roche, which reported $123 million and $472 million in sales of the drug last year, respectively. A Glaxo representative denied that the drug was responsible for the cases of liver damage, noting that the overweight are already at risk for liver disorders.
But the FDA has cautioned that all people taking Alli or Xenical contact their doctors immediately if they suffer any symptoms of liver damage, including fatigue, fever, nausea, vomiting, jaundice, brown urine or stomach pain. Loss of appetite, itchiness and light-colored stools may be signs of more advanced liver damage.
http://www.naturalnews.com/028902_Alli_liver_damage.html