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Acyclovir vs. Valtrex

I am in a committed relationship and my boyfriend is fully aware of the risk of HSV-2 transmission, however, I would obviously like to keep him infection free!  I just received a prescription for daily suppressive Acyclovir that I began taking today.  My outbreaks are minimal, so the primary purpose for the medication is to reduce the risk of transmission.  I have read in various places that Valtrex is the only suppressive medication that has been proven in clinical trials to reduce transmission.  I am under the impression, however, that this is simply because Valtrex is the only drug that has been tested for reduction in transmission.  

My question is....since Acyclovir also suppresses the HSV-2 virus, is it likely that it will also reduce the risk of transmission?  Or, is Valtrex a more effective drug and should I consider switching to that?
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101028 tn?1419603004
yes it is available as a generic now but if you don't have insurance, it's still way more expensive than acyclovir. same goes with famvir.

grace
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Avatar universal
I beleive valtrex is now available in generic in the US. I wold see if it s worth it
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101028 tn?1419603004
take 2 200mg at a time 2x/day - far more convenient :)

the assumption is, the less you are shedding the virus, the less chance your partner has of coming in contact with active virus. I myself don't pay the extra money for valtrex :)

grace
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Avatar universal
Thanks Grace, that's what I was thinking but it's nice to have a confirmation.  I'm actually taking 200mg Acyclovir 4x per day (simply because that's what my pharmacy had available). Very inconvenient, but much less expensive than Valtrex.

So, it sounds like if I take the Acyclovir as directed it will be as effective as Valtrex at reducing the risk of transmission.
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101028 tn?1419603004
acyclovir is 400mg 2x/day. is what what you are taking?

correct, valtrex is the only drug studied for reduction in transmission to a partner. acyclovir reduces shedding at the same rate , you just have to take it more often.

once daily valtrex is just more convenient, it's not better.

grace
Helpful - 0
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