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HSV II Test Results

I had an STD panel test done earlier this week, which included IGG tests for HSV 1 and 2.  I'm extremely low risk and didn't think I'd had the remotest possibility of having anything, but a new girlfriend wanted me to.  My last possibility of exposure would have been approximately four months ago.  My test came back as equivocal for HSV2 at 1.02.  

I was terrified and immediately signed up for another test (three days after the first).  This one came back as positive for HSV2 at 1.43.

Is there any chance of a false positive here?
Best Answer
3149845 tn?1506627771
Hi, testing positive twice with a low positive would be indicative of a recently acquired infection and 4 month could be considered a correct timeline for those numbers. Wait 2 months and retest.
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Avatar universal
You are having tests way to close together to really tell you very much. Not giving your body too much time for antibodies to climb or those 'junk' proteins causing a false positive to clear from your blood.

YI'm sorry but you need to settle back from the WB.
Helpful - 0
Avatar universal
I just received my girlfriend report and it was mentioned that

HSV 1 -IGG  0.56
HSV 1 -IGM 0.14

HSV 2 -IGG  1.74
HSV 2 -IGM 0.53

what does this mean ??? while the >1.2 is positive

and mine is test report is

HSV 1 -IGG  0.61
HSV 1 -IGM 0.12

HSV 2 -IGG  8.25
HSV 2 -IGM 0.48


So whom infected the other, while my girl friend doesn't suffer from anything while i am suffer most

1) My lumpnodes have swelling and i have pain in the joints and there was pimples on my rectum and this happen first on november on 2013 and now again happen on july 2014 what is the problem

and i was told by the dr. to have to zovirax 800mg twice a day  for a month.
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Avatar universal
While waiting for 16 weeks from my last exposure to run, I've done a few more IGG tests.  Here are my results to date, going back to when I originally tested:

7/14: 1.02
7/16: 1.43
7/18: 1.39
7/24: 1.29

Is it strange that my antibody levels are decreasing over time or is variation within that range to be expected of an early positive?  Getting in with an infectious disease doctor next week, but figured I'd ask since y'all have been so helpful.

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Avatar universal
I would be seeking a Westernblot 16 weeks after last exposure for confirmation.
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Avatar universal
And thanks for all your help, guys.  Really appreciate you taking the time to respond honestly and helpfully to me.
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Avatar universal
Yes.  Last exposure was 3/29, and she's very low risk too (two or three partners in the last few years).  No symptoms at all.  I just don't understand how this is possible.
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Avatar universal
Now when you say last possibility of exposure was 4 months before the test, do you mean absolutely no vaginal sex protected or otherwise in this period?

If this is the case then I find it harder to believe that you'd be climbing toward a positive result from a recent infection and would feel the odds of a false positive are quite strong.

I also suggest this as you do not indicate any genital symptoms at all, which would be a bit unusual given you have no prior HSV1.
Helpful - 0
3149845 tn?1506627771
Yes it would be considered conclusive but more for a person wit only 1 low positive. In your case, since even the best tests miss 10% newly acquired infecitons, even with a negative WB, test one more  to even out the score.
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Avatar universal
Is a negative WB similarly conclusive in your view, let's say 8 months from last possible exposure?
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Avatar universal
Nothing is "bad" until you know for sure you have something.

I agree with Life360.  Get re-tested in a few months for confirmation.  

If you get another "low positive" seek a Western Blot at 5+ months post exposure.  A positive WB is conclusive...

Good luck.  Keep us posted.
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Avatar universal
Negative on the first one, and i didn't re-test for 1.  Which I know is bad.
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Avatar universal
what were you HSV1 levels?
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Avatar universal
Great . . .
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3149845 tn?1506627771
Yes i would agree with one low positive but 2 does up the anti a bit.
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Avatar universal
Got it, thanks.  This post: http://www.medhelp.org/posts/Herpes/False-Positive-HSV-2-Igg-test-and-Western-Blot/show/2020094?page=1  said that 65% of sub-3.5 positives are false positives.
Helpful - 0
3149845 tn?1506627771
All i can say is that having 2 positives is quite compelling unless you  had a combination test.
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Avatar universal
Any chance of false positives or is that wishful thinking on my part?
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