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High Positive with Herpeselect, Negative for Biokit

I have been with the same boyfriend for 3 years. Either of us are experience any outbreak, but just a doctor recommend to check the STDs since I have the urine infection. As I known, herpes test usually not include in a routine check but they did it anyhow. The result came back in September 27
HSV 1 8.0 - positive (The result was from Herpeselect Kit from Focus Diagnostics, cross-reactivity with CMV, NZV, HHV6, and VZV viruses is possible)
I have had chicken pox vaccine when I was little. I'm not sure if that the cause for the positive result.
I went to the STDs specialist and have the  Biokit test (October 5), and the result came out negative.
Is there confirmed that I have negative? or should I run another any other test?
Best Answer
3149845 tn?1506627771
Im not following this at all. If you test values for hsv2 was 3 or below, this is a sign of a false positive and if you tested a second time with the biokit (which is hsv2 specific) then your negative. If you tested for hsv2 and had a value of 8 and retested and was below 1, something is  wrong here.
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Avatar universal
I have try to talk to the people at the lab, but they don't know that either. And I don't want to go back to the doctor because I don't think she know much about this topic, plus she's only a PA. I want to seek to a specialist .I have found this link about the Herpeselect test with cross-reactivity from Focus Diagnostics but I don't understand the number. Can you help to explain to me?
http://focusdx.com/pdfs/pi/US/EL0920G.pdf
Helpful - 0
3149845 tn?1506627771
Okay, lets take hsv1 out of the picture because you tested negative the first time.
Now we have hsv2, your first test was an 8 but we dont know if that included chicken pox strain. A second test came back at 2 with is indicative of a false positive.
The last test came back negative with biokit which is hsv2 specific. If you throw out the first test then your negative. If the first test was only for hsv2 at 8 and the zoster strain was included then your still negative.

You really need to find out about the first test at 8 if this included zoster herpes or not
If  you cant get that info and are still confused then take the Western Blot and put this behind you once and for all. But the evidence would say your negative for both hsv1 and 2.
Helpful - 0
Avatar universal
Sorry that I confuse you, this is what happen
1st test on 9/27 Herpeselect EIA igg HSV 1 is 0.2 and HSV 2 is 8.0 (there is also a note from under HSV2 test said that 'Cross-reactivity with taxonomically related viruses such as CMV, NBV, VCA, and VZV is possible)  I have chicken pox vaccine when I was little, that's why I assume this might cause the high number
2nd test on 10/4 at Quest Diagnostics with HSV 2 only and the result is 2.0
3rd test on 10/5 at a specialist STDs, with Biokit  for HSV2 and it came out negative. He knows about the result of HSV2 is 8.0 but he didn't know about the new result at the time.
I have concern about the number because it jump from 8.0 - 2.0. and I have no symptoms of outbreak, I have been with the same guy for 3 years and both of us never experience any outbreak. We are aslo have oral sex and intercourse sex. Would I be infect for both HSV1 and HSV2 though?
I am very confuse right now
Helpful - 0
3149845 tn?1506627771
talk to your doctor and let us know the results, the test they is very accurate. What you need to do now is get some clear value numbers from all the tests. Even here what you posted is confusing. You say your positive at 8 for hsv1 and then you say its o.8 and then you say thats its 2.0. You need to get your number clear and straight.
Helpful - 0
Avatar universal
The people at the lab said they can't interpret my result. I need to talk to my dr. I think they confuse as I do. They only said they used the EIA method. What should I do now?
Helpful - 0
Avatar universal
The people at the lab said they can't interpret my result. I need to talk to my dr. I think they confuse as I do. They only said they used the EIA method.
Helpful - 0
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