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Hsv type specific tests
Does anyone know how reliable the Euroimmun hsv igg elisa tests & the Calbiotech hsv igg elisa tests are??? Do you know about potential false positive/ false negatives?? Are they any good at diagnosing herpes 1 & 2. I know most persons are familiar with the herpes select but what about these 2????
Best Answer
Yes definitely. A 1.1 result is a very low positive and needs confirmation. The Euroimmun has done that.
Thank you so much for your comprehensive explanation. You really sound as though you know what you are talking about and you have put my mind at ease! I appreciate you taking the time to respond and explain it to me.
So you think I should disregard my first hsv 2 IgG result of 1.1 as a false positive and take the euroimmun hsv 2 IgG test of 2.66Ru/ml as a conclusive result that I am truly negative for HSV 2?????
So you think I should disregard my first hsv 2 IgG result of 1.1 as a false positive and take the euroimmun hsv 2 IgG test of 2.66Ru/ml as a conclusive result that I am truly negative for HSV 2?????
The euroimmun hsv elisa scale is different to the herpes select. It uses a range of 0.00-22.00Ru/ml. I read somewhere on this forum that grace said it was an inaccurate test?? Is this true???
I ask because I did an hsv2 igg and got 1.1
then I went to another lab using the euroimmun hsv2 elisa igg and I got 2.66 Ru/ml which uses the 0.00-22.00Ru/ml scale. Under the results was written: "negative serological testing but does not exclude the possibility of past hsv infection"
What does that mean????
The hsv 1 igg was >200Ru/ml and under this result it said: "previous or current hsv infection"
What do these results mean?? Do I have hsv2??
I ask because I did an hsv2 igg and got 1.1
then I went to another lab using the euroimmun hsv2 elisa igg and I got 2.66 Ru/ml which uses the 0.00-22.00Ru/ml scale. Under the results was written: "negative serological testing but does not exclude the possibility of past hsv infection"
What does that mean????
The hsv 1 igg was >200Ru/ml and under this result it said: "previous or current hsv infection"
What do these results mean?? Do I have hsv2??
These tests are fine. The Euroimmun has been reconciled against a Herpeselect and performs very well.
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Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.
In theory the Euroimmun is more accurate as it interpolates a result from three control points: 2 Ru/mL, 20 and 200. Herpeselect has just one reference value. The Ru/mL is a quasi measure of antibody but in the end should be read more in terms of the reference ranges. Greater than 22 is positive but most positive people test >50.
You are positive for HSV1 and negative for HSV2. The disclaimers refer to the time period for antibodies to form. Usually it says that test cannot rule out recent infection. This is why 12-16 weeks post exposure is required for any HSV IgG test to be conclusive.