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Avatar universal

can a positive swab but negative western blot happen?

I have a few questions:

1. If someone has a positive swab, but negative western blot, does that mean its still herpes?
2. If someone has a low IGG (less than 3.5). negative western blot, positive swab, is that even possible? If so, why does that happen?
3. If someone has a low IGG (less than 3.5), but consistently negative western blot, is that a correct result?

I have a low IGG, and I am waiting for the western blot test result. I could not swab test since it was scabbing already. But can #2 for some people?
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Avatar universal
Are you sure it was an IgG test.

Each test has a different control level and some manual procedures such that variations are normal and to be expected.

It is hard to speculate, I know Howard suggested this looks like a new infection but I'm not quite in that camp yet.

You have done all you can and wisely sought the Westernblot. Let's work on those results when through. This should be any day now?
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Avatar universal
And when I tested the same iGG test for 1 and 2 there was a month gap..1.85 to 1.87. The third test was done at a different place, and I dont know what test it was.
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Avatar universal
Thank you very much for the explanation! I would like if they could explain the results IF it is negative!

The only reason my alarm bells having been ringing is when I took the third test..I could not believe the hsv 2 jumped from 1.87 to 3.1..there was a 9 day between them. I could not get a copy but the numbers were told by someone on the phone and that was it.
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Avatar universal
OK let's zero in on the issues here.

You most probably have had HSV1 since your youth and happened to have a breakout in January.

Your June tests confirm that you did not have HSV2; you never received it from any sexual encounter up to January last year.

Your October encounter was very low risk of HSV2, if any at all.

Your Westernblot should technically be taken 16 weeks post the encounter but I think 12 weeks will tell us what we need to know. If you are truly positive and triggering an IgG test, then there is every likelihood you'll trigger a positive on WB.

A negative will in my view be sufficient. You could ring to discuss the results for confirmation. People who are falsely positive on IgG trigger one of the several bands of antibodies by size that the WB looks for but are non existent on the others. Your results are individually reviewed by a scientist and many are willing to have a constructive conversation about your results.
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Avatar universal
Btw the June tests were:

hsv 1 >6
hsv 2 <0.90
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Avatar universal
Sorry if I am going everywhere, I am very frustrated by this and I cant believe anything.

I had vaginal sex last year January, and two weeks later I got cold sores on my lips. Since then I have not had any contact except for this encounter..I am trying to figure if those scabs were hsv 1 or 2. I tested last June, and I came back positive for 1 but negative for 2. Thats why this is worrying for me.

I did see two other scabs in a different place later on but I think that is friction..I dont know if these scabs are friction as well. It could be possible that hsv 2 is acting up now?
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