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Avatar universal

IGM vs IGG

Hello Feelingundone and fleetwood.

when you get a chance, could you please answer below.

Let's say if 'XYZ' Person has HSV due to recent Oral Sex (could be 1 or 2). And XYZ person's initial IGM test results are Positive.(Please consider in this case IGM is accurate) and my questions are.

1) How long Immune System keep IGM Antibody as Positive?
2) Does Immune system keeps either IGM or IGG (1 or 2)  at least one of them keep Positive during complete life time?
3) is there any possibility that Person XYZ's Immune system First produce IGM Antibody i.e, Positive, and change  to Negative after couple weeks  but still IGG is negative. Is there such case?
4) I assume either on of them whether  IGM or IGG should be positive if a person diagnosed with HSV. Do you Agree?  

4 Responses
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Avatar universal
Thanks Doctor, I have already ordered IGG type specific not IGM and i will schedule for test this week. Will Keep you posted.
Helpful - 0
1 Comments
Hello Doctor,

I got my test results at 8th week tested.
Both came as negative, but thing is there is no values, all it shows lessthan 0.9 value.

I have contacted quest diagnostics but they said they do not have values with them.

Please let me know what is my next action plan. Would like to follow under your guidence.Can i go get tested again after 4 weeks?

Erased my personal information and attaching just test results.
15249123 tn?1478652475
You can test at 8 weeks. It will be a good indicator. No igm tests.
What you describe is not hsv related. Let me know the results.
Helpful - 0
Avatar universal
Thanks doctor, I'm trying to keep myself busy but I can't ,my brain not listening me. From tomorrow I'm on my eighth week, can I go get tested for IGG type specific? I can't wait.

I know you said it's not herpes I want to update here, I had small bump on June-14 on top left side of lip it appeared without pain and after 5-6 hours later I see white pus formed but everything disappeared in two days. But I never had such pimple on my lip. Could be my body has more resistance power to heal so quickly is that possible???

Sorry doctor keep on asking samething repeatedly but I thought of updating here so I feel some relief.  

Helpful - 0
15249123 tn?1478652475
The body would produce the antibodies the igm test for shortly after infection. A week or two. They don't  stay very long in most people.

2. Yes the igg should remain positive for life. Hsv1 testing isn't  perfect  and can miss an established infection. Hsv2 does not have that issue.

3.igm would in most cases not stay positive but once the igg is positive  there is no reason to test for igm.

4. No. I do not put any faith in the igm test. If you had a newly acquired hsv1 infection of the genitals and didn't  have a previous oral infection you would surely know it.

We had a lengthy discussion on the subject. You do not have hsv. Forget about the igm test it is NOT RELIABLE at all. You had a super low risk encounter with  even lower risk partner. I can not stress that enough. You are fine and it's  time to move on without concern!!!
Helpful - 0

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