I was exposed to a wart 16 years ago. No problems for years, and never broke out. The past 5 years in that exact area I have experienced chronic inflammation on my vagina. I have had the area biopsied two times. The first time the biopsy results were "squamous pappiloma w/chronic inflammation" the 2nd "chronic inflammation w/changes associated with HPV" . These biopsies were taken one year apart, so the cells are "changing." After the 2nd biopsy my GYNE gave me Condilox (sp?) to apply 2x per day for 3 days, then off for 4 days, repeat for 1 month in hopes of putting this into remission. It caused sores, pain, and felt like a cigararette was being extinguished onto my vagina. The area this inflammation is described as if my vagina was a clock, it is between 5:00 and 7:00. I have seen 4 gynecologists, a dermitologist and my GP. I have abstained from vaginal sex for 6 week stretches to get the inflammation to "settle down". Since this Condilox it seems it has been worse than ever. My last two Gynecologists are from Rush and Northwestern, I am traveling to the Chicago to get state of the art care....but it seems there just isn't a straight forward answer on what to do to stop the inflammation, short of surgery. Risks are that it can cause scar tissue and make matters worse, which I am not interested in doing unless it becomes cancer. I think the inflammation can go away at some point, but surgery is permanent and I will live with those consequences. Another option I have been presented is to take a antidepressant which has a side affect of helping women with vaginal discomfort. I really don't want to do that, I have never taken anti-depressants and feel that this is simply masking symptoms that my body is telling me something is wrong. I fear if I cannot feel pain, I may be making matters worse! I take multi-vitamins, do not do drugs, do not smoke, drink alcohol socially. I have tired Acai Berry juice and other "fads" in hopes of helping matters. I have given vaginal birth to my 2 children. This area is where the episiotomies were, and wonder if that is what "woke up the monster". I have been married for 14 years and monogamous - this is strenuous on our sex life - as I avoid sex most of the time. We have had vaginal sex less than 5 times in 9 months - it just hurts too much. It feels like there is a blister or open sore that is being scratched when we have intercourse. This has affected my marriage and is affecting me mentally. I miss my husband and our intimacy and cry in fear of pain of sex and both of us are stressed when we do have vaginal sex - he is afraid to hurt me, I am afraid it will start to hurt if he doesn't "hurry." I am tired of being in pain all of the time. I am afraid that this will never stop and I will have to live with this the rest of my life. I am hopeful someone out there has been through this and can give me some advice.