inverted papilloma in nasal passage

[GaHoosier]

I am 59 years old and diagnosed with inverted papilloma in nasal passage in Sept. 2009, which was removed in Oct. 2009.  A few months later it returned and I will be having surgery again to remove it.  According to everything I have read about it, there is no concensus about what causes it to occur in the nose or sinuses.  Apparently it recurs frequently.  I am interested in hearing from anyone else who has experienced inverted papilloma of the nasal passages and what treatment they have had.  

[Struggling111]

Hi, sorry for your diagnosis, how are you going now an update of how you’ve been for last 8 or so years if this thread is still active? Did you ever find out which hpv strain caused the nasal papilloma? My strain has never been confirmed but only picked up through the new hpv Pap smears screening that came out last year in my state. I have not had any visible complications to date but uncomfortable symtpoms which cannot be explained and only a diagnosis of high risk

[dnr530]

I'm 28 years old. I was originally diagnosed with IP at 17 years old. Over the span of 11 years, I've had 5 surgeries: one was a biopsy alone, the  endoscope resection, then another endoscopic resection and lux Caldwell incision. After that surgery, I had no recurrence for 6 years. I then had a recurrence and surgery in April of this hear and was just told in June it has come back again in a very small place. Being that my condition is benign with no sign of malignancy or dysplasia, my ENT reccomened we moniter it's growth for 3 months. I plan to undergo anther surgery at that point and hopefully I have no recurrences. If anyone has any questions or needs any support with thus condition feel free to email me at ***@****. There is very little info online so you may find my insight helpful.

[Struggling111]

Hi, after the surgeries you’ve had were they biopsied for hpv? And do you know which high risk strain? As you were diagnosed so young at 17 the first time you would assume your hpv transmission was not transmitted through sexual contact but possibly at birth from your mum maybe? Has she ever been diagnosed as high risk hpv? I have high risk hpv and am currently having pregnant, I know the studies say it’s rare but possible to spread hpv to bub, I heard they can develop throat hpv from in the womb and have troubles later in life, as may be the case with you I’m not sure. I worry about my partner getting throat cancers or other and myself with the vange of complications high risk can cause. How are you going now? Take care

[dnr530]

They were tested only for malignancy. I intend to be check for HPV on my next surgery.  To my knowledge, my mother doesn't have HPV. From my research, IP is not always caused by HPV. I suspect I may have HPV 6 or 11 because I have had non genital skin warts in the past. The overwhelming majority of people who get HPV clear the virus naturally by their immune system. A small percent can't fight it off and intern get symptoms such as polyps, warts, cancer etc. I was born by C section so I doubt I got any HPV transmitted to me. I will note I also have an identical twin brother who has no IP.  You must remember, nearly all people get HPV of some type during their lives, and normally it's cleared by the body. Also, not all IP exists with HPV. Some medical journals I've read suggest the initial disease is caused by HPV which is them cleared by the body over time, but the papilloma stays.  I'm doing well now, no real issues other than numbness from surgery and facial pain sometimes. I do have a small place of reccurance which i will have removed my ENT reccomened we moniter it's growth. He will have to make an external incision to access the spot so we are monitoring it 3 months to assure no recurrence in another area. Thanks and Best wishes!

[NewHPVcase]

What were your symptoms at the original diagnosis.

[DwightSight]

I had my 2nd surgery to remove IP from my right nasal sinuses.  They took pieces of sinus and bone out to go after the root, but they also noticed some growth that was too close to my brain to remove using endoscopic surgery.  I'll have an MRI in about 6 months to re-check, and may have to have major surgery (i.e., cut open my face to get at it).  Not looking forward to it, to say the least.  

Can IP be caused by oral sex with a woman who has HPV?  Is it hereditary?   I have no idea.

[ShannWX]

I just stumbled upon this thread while searching for general IP info. I'm 25, and my (left side) nasal IP was diagnosed/discovered in 2003 when I was 17. It's been partially removed twice, and my third surgery in seven years is tomorrow morning. My previous ENT doctor told me that total removal was impossible -- which is, apparently, untrue. My new ENT intends to remove it totally, though this does involve removal of part of the lower concha, and some skin (which the IP has grown against).

Regarding treatment, both surgeries have been partial resections done endoscopically. Tomorrow's surgery will be endoscopic as well, but we're aiming for total removal.

No one's sure what causes IP, though the prevailing thought is, of course, that it's caused by a strain of HPV -- though what triggers it into action/growth is unknown, as is, insofar as I know, what strain causes it or how said strain is transmitted.

Anyway, I hope your second surgery went well and that you haven't had a recurrence.

[Som_Meh]

Hi , I know it been 6 years after your comment but I would like to know what happened after.

[GaHoosier]

Thanks for your input.  I have CT scan tomorrow and see surgeon next Monday.  I will let you know what I find out.

[Tom_123]

I'm not sure you'll find much experience here, I seem to be the only respiratory papilloma sufferer right now. There is, however a great wealth of support and collective knowledge, so keep posting and please share what you learn.
From the American journal of Oncology.........
The preferred treatment of inverted papilloma is surgery; postoperative radiotherapy is added if it is associated with squamous cell carcinoma. The likelihood of local recurrence after surgery for inverted papilloma may be substantial and varies with the extent of resection.