Blisters on the palm

[agnesC]

Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it? agnesC

[agnesC]

Thanks for your very prompt and precise feedback. Blisters are not severe enough to disturd normal day to day operations. Just hope it doesn't get any worse. Regards agnesC

[PaulMD]

Hi there.

This is a common side effect of gleevec and any other drugs in the same class for that matter.  The mechanism behind this side effect is still not completely understood.  Some blisters can be so severe that they can affect a person's function and can really be debilitating.  

I believe that this would warrant an evaluation by your doctor, and probably decrease the dose of the drug or to discontinue this temporarily until the lesions resolve.  It is important to maintain the hydration of the skin through moisturizers and avoid puncturing the blisters.

Regards and God bless.