Suspicious of Follicular lymphoma

[satya17]

I have done all the test below. please suggest the severity of the disease and treatment plan.

Also suggest any further tests to be done.

TATA MEMORIAL HOSPITAL
Dr.E.Borges Road, Parel, Mumbai 400 012
Tel: [phone] Fax: [phone]
E-mail:***@**** Website:tmc.gov.in




Case No. :CN/07375  Patient Name :Mr. SATISH GOPAL RAUT  
Reg. Date :9/3/2016  Sex/Age/Catg. :Male /37 yrs/ Gen-C  
Status :Outpatient  Pri. Dr./Unit :DMG ADULT HEMATOLOGY  




All Requisitions


Requisition No. Reqn Date Modality Service Description Reqn status Report Date
FZZSP16012714 09/03/2016 SP Outside unstained slides with or without blocks (except lymphnode & breast) FinalReport 14/03/2016  
UZZHL16086938 09/03/2016 HL M.SERVICES FinalReport 10/03/2016  
UZZHL16086939 09/03/2016 HL M.SERVICES FinalReport 10/03/2016  
FECBC16073922 09/03/2016 BC M.SERVICES FinalReport 10/03/2016  
GZZSE16009805 09/03/2016 SE M.SERVICES FinalReport 10/03/2016  
FZZSP16012715 09/03/2016 SP Small biopsy/cell block except lymph node & breast FinalReport 15/03/2016  



  

Final Histopathology Report for requisition no. FZZSP16012714  
Reqn. Date :09/03/2016 Consultant Pathalogist : EPARI SRIDHAR
Report Date : 14/03/2016 Resident Pathalogist :PRANJAL GUGALIA
Sample Rec. Date : 09/03/2016 Path. no. :010744/CN  
Previous Path No. :010744/CN  010820/CN  
Nature of Material Received :2 paraffin blocks (JH-222/16)  
Service Desc. :Outside unstained slides with or without blocks (except lymphnode & breast)  


Microscopic Description:-

Retro orbital mass biopsy (side not mentioned - 2 paraffin blocks):

Dense lymphoid cell infiltrate showing vague follicular architecture with germinal centres and relative expanded mantle/marginal zones.
Interfollicular areas with sheets of relative monocytoid-like cells seen.
On immunohistochemistry, the expanded zones mantle/marginal zones are positive for CD20 and Bcl-2; CD138 does not reveal any plasmacytic differentiation. Cyclin D1 is negative. CD3 reveal sparse interfollicular T-lymphocytes. MIB-1 reveals high proliferating germinal centres and 5% in the expanded mantle/marginal zones.




IMPRESSION:-

Retro orbital mass biopsy (side not mentioned - 2 paraffin blocks):

Low grade B-cell non-Hodgkin lymphoma, favour marginal zone lymphoma.








  
Final Report for requisition no. UZZHL16086938
Reqn. Date :09/03/2016  Report Date : 10/03/2016 Report By : P G SUBRAMANIAN  
Service Desc. :M.SERVICES  


Investigation Observed Type Observed Value Normal Range
1. eosinophils % High 8.0                    1.0-6.0 %
2. neutrophil % Normal 58.8               40.0-80.0 %
3. Basophils % Low 0.5                       1.0-2.0 %
4. Basophils abs Low 0.0325                0.02-0.1 x 10e9/L
5. Eosinophils abs High 0.52                 0.02-0.5 x 10e9/L
6. HB Normal 14.3                               13.0-17.0 g/dL
7. HCT Normal 40.8                             40-50 %
8. Lymphocyte % Normal 25.1             20.0-40.0 %
9. Lymphocyte abs Normal 1.6315          1.0-3.0 x 10e9/L
10. Monocyte % Normal 7.6                     2.0-10.0 %
11. Monocyte abs Normal 0.494               0.2-1.0 x 10e9/L
12. Neutrophils abs Normal 3.822              2.0-7.0 x 10e9/L
13. NRBCS % Normal 0.1                      0.0-2.0 NRBCS/100
14. RBC Low 4.32                              4.5-5.5 x 10e12/L
15. TLC Normal 6.5                          4.0-10.0 x 10e9/L
16. MCV Normal 94.2                              83-101 fL
17. MCH High 33.1                              27-32 pg
18. MCHC High 35.1                          31.5-34.5 g/dL
19. RDW Normal 13.3                      11.6-14.0 %CV
20. PLATELETS Normal 202               150-400 x 10e9/L
21. MPV Normal 8.0                               7.5-10.5 fL

  

  
Final Report for requisition no. UZZHL16086939
Reqn. Date :09/03/2016  Report Date : 10/03/2016 Report By : P G SUBRAMANIAN  
Service Desc. :M.SERVICES  


Investigation Observed Type Observed Value Normal Range Control Machine
1. APTT  Normal  29.000                       29.5 ELP03
2. INR  Normal  1.034                         ELP03
3. PT  Normal  13.800                        13.4 ELP03

  

  
Final Report for requisition no. FECBC16073922
Reqn. Date :09/03/2016  Report Date : 10/03/2016 Report By : P.K. SADHUKHAN  
Service Desc. :M.SERVICES  


Sno Procedure Name Observed Type Observed Value Normal Range
1. Fasting Blood Glucose  Normal  78              70-99 mg/dL  
2. Serum Urea  Normal  19                              12.84-42.8 mg/dL  
3. Serum Uric Acid  High  9.0                           3.5-7.2 mg/dL  
4. Serum Creatinine  Normal  1.2                    0.7-1.3 mg/dL  
5. Serum Sodium  Normal  139                     136-145 mmol/L  
6. Serum Potassium  Normal  4.2                  3.5-5.1 mmol/L  
7. Serum Chlorides  Normal  106                  98-107 mmol/L  
8. Serum Bicarbonates  Normal                   22.9  22-29 mmol/L  
9. Serum Protein  Normal  7.3                       6.6-8.3 g/dL  
10. Serum Albumin  Normal  4.3                    3.5-5.2 g/dL  
11. Serum Globulin  Normal  3.0                     1.7-3.5 g/dL  
12. Serum Alkaline Phosphatase  Normal  71   30-120 U/L  
13. Total Bilirubin  Normal  0.63                        0.3-1.2 mg/dL  
14. Serum AST  Normal  19                             < 50 U/L  
15. Serum ALT  Normal  30                               < 50 U/L  
16. Serum LDH  Normal  190                               100-190 U/L  
17. Serum Calcium  Normal  9.1                           8.6-10 mg/dL  
18. Serum Phosphorus  Normal  3.8                      2.7-4.5 mg/dL  





Final Report for requisition no. GZZSE16009805
Reqn. Date :09/03/2016  Report Date : 10/03/2016 Report By : SANJAY BISWAS  
Service Desc. :M.SERVICES  

  
REPORT:-
TEST RESULT
Hepatitis B Surface Antigen (HBsAg) NonReactive
Hepatitis C Antibodies (Anti HCV) NonReactive
HIV Antibodies NonReactive
  

      

  

Final Histopathology Report for requisition no. FZZSP16012715  
Reqn. Date :09/03/2016 Consultant Pathalogist : EPARI SRIDHAR
Report Date : 15/03/2016 Resident Pathalogist :PRANJAL GUGALIA
Sample Rec. Date : 10/03/2016 Path. no. :010820/CN  
Previous Path No. :010820/CN  010744/CN  
Nature of Material Received :Bone marrow biopsy  
Service Desc. :Small biopsy/cell block except lymph node & breast  

Gross Description:- Received single linear bony bit measuring 1.2cm in length submitted entirely.



Microscopic Description:-

Bone marrow biopsy:
Normocellular marrow for age (approximately 40-50% cellularity) with hematopoietic cells of all three series.
No tumour deposit seen.




IMPRESSION:-

Bone marrow biopsy:
Normocellular uninvolved marrow.