I had a hysterectomy last September 2006. I have been taking Synthroid since 1995. All of the sudden, the estridol patch I now use and the synthroid seem to be battling it out to see who is going to win. Now when I take my synthroid I get nervous, sick in my stomach, jittery, tremors, etc. and I can't even take the medication and function any more. I have just decided to give up on the patch because I feel like a zombie every day. Why would I get these symptoms from the synthroid all the sudden? Do menopause and thyroid have something to do with eachother? I went off the synthroid too because I just couldn't take it any more. Now my TSH levels are 80.00 but I am not having any symptoms of an underactive thyroid. What is going on?????