slinia, I have tested positive for the virus, even before I started Ty; your neuro will probably keep a close eye on it.
I don't know what I will do if tysabri stops working or if I get the JC virus. I have been on Ty for 6 years. So far I'm doing good.
Hi SCG -
That they showed up early may be a good thing. From rxlist.com:
"Antibody testing: If the presence of persistent antibodies is suspected, antibody testing should be performed. Antibodies may be detected and confirmed with sequential serum antibody tests. Antibodies detected early in the treatment course (e.g., within the first six months) may be transient and disappear with continued dosing. Repeat testing at three months after the initial positive result is recommended in patients in whom antibodies are detected to confirm that antibodies are persistent. Prescribers should consider the overall benefits and risks of TYSABRI in a patient with persistent antibodies."
As to what comes after Tysabri, for me it's RItuxan (rituximab). After 20 infusions Tysabri stopped working. I switched to Rituxan about a year ago and it seems to be doing the job.
It's important to remember that no DMD is designed to relielve symptoms. Their purpose is to stop/slow further relapses. Current symptoms are often addressed by other meds, but DMD's are meant to slow MS down.
Kyle
I've been on Tysabri since 2012 and tested + before I started. Some months I feel better, some I don't.