Both are prescribed for spasticity in MS. I've only been on baclofen, but my understanding is that Zanaflex would work quicker and short term where Baclofen would work in the system gradually and hope to provide more long term effects.
I can't speak to the difference in the mechanism by which they work but this is my general understanding.
When I was prescribed it I wanted something that I could pop and have it work, but the doc said he wanted to get out ahead of the problem, and started me on the baclofen.
I just started the zanaflex, and so far seems to help. It takes the problem away slowly but at least I am not all stiff and unable to move. I normally take it at night due to the fact that it can make you tired, but I have had to take it during the day and did not make me any more tired than I already am.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.