CSF results. MS?

[xxSamanthaJ]

I am in the process of getting some of my results back from my lumbar puncture to test for MS.

Any help would be greatly appreciated in understanding these and which ones i should be worried about.

My one question is, ive seen the standard ranges vary from person to person, how does this work, and how do i know the standard range is correct??

IGG INDEX, CSF + BLOOD

IgG (serum) my value: 1200     standard: 694 - 1618   mg/dL
Albumin (serum) my value: 4.6     standard: 3.7 - 5.1    g/dL
CSF IgG my value: 2.5       standard:  0.8 - 7.7   mg/dL
CSF Albumin my value: 18.4   standard:  8.0 - 42.0    mg/dL
CSF IgG Index  my value: 0.52   standard:  <0.66
CSF IgG Synthesis Rate  my value: -2.9  standard:  -9.9 - 3.3  mg/24h

CSF Protein my value: 47  standard:  15 - 45 mg/dL     H


GLUCOSE, CSF - LAB
CSF Glucose my value: 56  mg/dL
-Reference Range: concentration of Glucose in CSF is about
60-75% of that in corresponding plasma.

CSF Angiotensin-1-Conv Enz   my value: 10     standard: <=15  U/L

CSF VDRL   my value: NONR      standard:  Nonreactive


CSF Lyme Antibody
SEE BELOW

LYME DISEASE AB [IgG],IFA <1:4
B BURGDORFERI IgM, IFA <1:1
INTERPRETATION
ANTIBODY NOT DETECTED
REFERENCE RANGES: IgG <1:4
IgM <1:1
Diagnosis of infections of the central nervous
system can be done by demonstrating the presence
of intrathecally-produced specific antibody.
However, interpreting results is complicated by
low antibody levels found in CSF, passive
transfer of antibody from blood, and contamination via
bloody taps. The interpretation of CSF results
must consider CSF-serum antibody ratios to the
infectious agent. However, demonstration of class
specific antibody IgM in CSF may be diagnostic.
The intrathecal synthesis of Lyme disease
antibody is most accurately measured by
performing the Lyme Disease Antibody Index
for CNS Infection.


these are all ive gotten so far other then me WBC count which is 3 out of 3-5.

any help would be great! thanks for your time and god bless!

[xxSamanthaJ]

diagnosed with fibromyalgia yesterday. i am still getting the western blot test done to test again for lyme, and then to see the MS specialist in december to make sure i dont have MS.

[SarahL2491]

yes you can have both

[xxSamanthaJ]

oh boy. i didnt know they did that test to see where you feel the pokes! ahh

I am still wondering if i should go to the MS specialists even if i do get a diagnosis of fibro next week. i could still have MS right? should i still meet with the specialist for MS in december?

[SarahL2491]

well there are diagnostic tests for fibro, the great "poke" you in 18-20 places and see how many times you yell "ouch that hurts"
be sure and google tests for fibro, its very interesting

[Ricobord]

Sounds like you are working all possibilities, which I think is wise. It takes too long to do work ups for one of these conditions at a time and you could decline while waiting.

When I suspected Lyme, I still went through the MS work up because multiple doctors recommended it. It was helpful to have an MS specialist say that I didn't have it so we could put it to rest.

That is great that your doc agreed to the IgeneX test. It should be helpful. False negatives are possible there, but less common. If you have been sick less than a year, odds are good it will show signs of Lyme if you have it.

I have the hesitancy when urinating, too.  You can see why it can get so tricky to differentiate between these conditions. While the underlying cause is very different, the outward presentation can be very similar.  Fibro should be the diagnosis of last resort, after eliminating everything else, as there are no tests to confirm it.

If you do have Lyme, heat can help ease pain. (Many pain killers don't help with Lyme pain, but different people respond differently.). I used a heating pad for my abdominal pain.  Just be careful not to lie down on the heating pad as it can burn you without you even realizing it.

I hope you get an answer soon!

[SarahL2491]

you are really sounding like fibro, and surely some baclofen and neurontin will make you feel better.  check with your neuro or rheumy about those.

good luck and keep us posted, we all learn from each other

Sarah