FDA approves PML test

[Lulu54]

The screening test for the JC Virus for patients considering Tysabri as their tretment was officially approved by the FDA today.  The test tells if the person has been exposed to the JC Virus or not.  PML on tysabri has only occured in people who are JC positive.  There has not been a single case of PML in JC negative people. You can read the release here-

http://www.medpagetoday.com/Neurology/GeneralNeurology/30774

[maxthecat9196]

I know of someone who tests positive for the virus.  She and her doctor have decided that she is ok to continue to take Tysabri though.  There must be other variables...

Tammy

[Lulu54]

It seems like I know few people who have tested positive for JCV.  For the stats being this disportionate, I think we all are indeed a fortunate group.

[Guitar_grrrl]

I've been tested twice in the last year, and they were both negative.  Since you can acquire JCV at any time, I opt to have my status tested once a year since I'm on Tysabri.  There is also a Tysabri antibody titre available, now.  I plan on doing that once a year, too, although development of Tysabri antibodies is relatively rare.

[meg321]

yes, I had that test and if I needed to switch, it would be okay.   My Dr was thinking ahead when we thought i was allergic to copaxone.   I am taking part in a study that I signed up for at the same time.

I cannot remember what it is ..my MO nowdays !

meg

[Lulu54]

The test does not eliminate anyone from taking Tysabri.  What it does do is makes the doctors aware that this patient is at higher risk for PML and they should be momitored closely while on Tysabri.  I;m glad to hear she is doing well - I hear great things about Tysabri.

BTW I did the test and tested negative.  65-70% of people with MS test positive for the JC Virus. JC is because that is the initials of the first person this virus was see in.

[Deb61]

I wonder if you can still get treatment with Tysabri if you test positive for the JC Virus.  My sister has been on Tysabri for three-four years now and is positive for the JC Virus.  She's got nothing but great things to say about the drug . . .