Aa
Aa
A
A
A
Close
1260255 tn?1288654564

For those Dx'd- What was your IgG index?

For those of you who have been dx'd with MS and went through CSF testing, do you know what your IgG Index was?

A high IgG Index has a strong correlation to MS, even in the absence of O bands. I just got my CSF test results back. Both the CSF and Serum IgG levels were low, but the albumin levels were within normal range. My IgG Index is .51, with anything below .66 considered normal. I did see one graph with a small percentage of people diagnosed with MS whose Index was between .5 and .6.

Also, if anyone out there knows how stable the serum Albumin level is, that would be useful information for me. I had an extensive panel of blood work done on 4/27/10 and the albumin level was 5.3 or outside of the 3.5-5.2 range. The LP was done on 5/4/10 and the albumin level one week later was 4.6. Of course this could be due to different laboratory tests.

Audrey

5 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Q,

can the IgG index value vary ofver years for MSers?

that is, is it possible to have a high IgG index when the onset happens such as with CSF infection & spine injury/trauma, then o-bands appear...then years later, still have the obnads but the IgG index isn't a remarkable value?

Helpful - 0
Avatar universal
1986:
the second LP from the san diego naval hospital shows IgG index calculated at 1.95 with o-bands but doesn't say how many o-bands, and with increased wbc in csf.

2009: the fourth LP shows a IgG index i think in a normal range but with more o-bands

U2





Helpful - 0
147426 tn?1317265632
One O-Band

IgG Index = 1.89

None of the other numbers concerning albumin and IgG levels are important.  They are all just needed to calculate the Index.

Q
Helpful - 0
198419 tn?1360242356
Hi there,

I don't have my report in front of me, but I believe mine was w/in range. I did have 0 bands in CSF though.

Once i dig it out, I'll post it.

giving this a bump!
Helpful - 0
667078 tn?1316000935
My CSF IgG index was 1.69
      CSF IgG   8.43
      12 o-bands
       CSF/albumin ratio O.46 CSF IgG synthesis rate 29.36

The blood serum was all normal and no o-bands

Albumin 3.7   (3.5-4.8) range

I guess different labs have different ranges.
Helpful - 0
Have an Answer?

You are reading content posted in the Multiple Sclerosis Community

Top Neurology Answerers
987762 tn?1671273328
Australia
5265383 tn?1669040108
ON
1756321 tn?1547095325
Queensland, Australia
1780921 tn?1499301793
Queen Creek, AZ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Find out how beta-blocker eye drops show promising results for acute migraine relief.
In this special Missouri Medicine report, doctors examine advances in diagnosis and treatment of this devastating and costly neurodegenerative disease.
Here are 12 simple – and fun! – ways to boost your brainpower.
Discover some of the causes of dizziness and how to treat it.
Discover the common causes of headaches and how to treat headache pain.
Two of the largest studies on Alzheimer’s have yielded new clues about the disease