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Recently, my neurologist told me that I still have enhancing lesions on my brain.  I wanted to know if anyone can tell be what is the definition for enhancing lesions.  I have attempted to look it up via email to no success. There are attachments like to a disease.  But, if you have not been diagnosed that is hard to do.  Tie it to a disease I mean.  Can anyone help?
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2015036 tn?1332997788
Have you read the health pages topic:  "How MRI's Show Lesions in MS?"

There should be something in there to help...

987762 tn?1331027953
Hi there,

I understand that 'active' lesions will light up (enhance) with the contrast thats injected for the MRI, inactive or the fully scared over lesions will not. When this happens its showing demyelination is happening, myelin is the fatty protein that is around the axons of the nerve cells, basically evidence that the blood brain barrier is compromised.

There isn't many conditions that will do this, MS is one but there are some others, but if your young MS is the more common, I believe.

1831849 tn?1383228392
I'm with JJ. My understanding is that all lesions will show up without contrast. When the contrast agent is added, those lesions that are currently inflamed will light up. Older lesions will not appear any differently in the presence of the contrast agent. For this reason MS MRI's are most frequently done both with and without contrast. It helps establish "dissemination in time" which is part of the MacDonald DX criteria.

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