I'll disagree with atacker, and say that my lumbar puncture was terrible - honestly, if your doctor is willing, I'd request a Valium or Xanax or something (and I've had two kids with epidurals, so I thought it would be a piece of cake).
Anyway... From what I've read there is a "typical" pattern for MS lesions is:
-MS plaques display T2 hyperintensity
-Lesions may be observed anywhere in the CNS white matter
-Typical locations include the periventricular white matter, brainstem, cerebellum, and spinal cord.
-Ovoid (oval in shape) lesions perpendicular to the ventricles are common in MS and occasionally are called Dawson fingers, which occur along the path of the deep medullary veins.
-Most specific lesions for MS are noted in the corpus callosum at the interface with the septum pellucidum.
But, as anyone in here can tell you, there is no such thing as "normal" when it comes to MS. It can manifest itself in thousands of different ways, and just as no two person's disease will progress in the same manner, no two person's lesions look exactly alike either. Some people have lots of lesions and little effects from them, some people have lots of lesions and lots of disability, and some people have one one or two lesions and have a lot of problems from them... there is no telling.
And then there's the people (like me) that don't even have the O-bands show up in their puncture, but everything else points to MS.
This link has a lot of great information and images of different types of lesions on it:
And Quix has several very insightful and educated posts about this kind of thing. They are well worth reading. ;-)
Wishing you lots of luck for a non-painful LP and some answers for you!