New article on MS

[Lor301]

Not sure about the validity of this study but thought i'd share it...

http://m.huffpost.com/us/entry/5288927?ncid=txtlnkusaolp00000592

[Guitar_grrrl]

I'm hoping this sort of discovery gets us closer to finding an actual cause, and not just developing a pharmaceutical band-aid, for MS.  I glad to be on Tysabri.

[Quixotic1]

Very interesting and genetic studies led to the discovery of this possible biomarker.  We have seen potential markers before that led to nothing, but this looks promising.  The protein in question is involved in regulating which immune white cells get across the blood-brain barrier to be able to cause inflammation in the brain.  Women appear to allow more of the very inflammatory cells across - T-cel lymphocytes.

This fits in with Tysabri's mechanism of action.  Tysabri blocks T- lymphocytes from passing across the barrier from the blood into the brain.  Tysabri is probably the most effective of all the DMDs discovered to date.  So it does correlate with the new findings in the article from the Huffington Post.

This does not prove anything, nor does it speak to why the T-cells are drawn to the brain in the first place.

Very interesting,  Thanks for the info.

Quix