I don't know how to reduce stress either, because life just simply is stress. I agree with Alex, finding a counsellor who spealizes in chronic illness is very helpful. And some sort of meditation, yoga, or something along those lines help too.
Stress can always aggravate sx's and pain, so it is important to find ways to help relax you. I do massage therapy and acupuncture, and see a counsellor. I have a major surgery scheduled for the 30th of this month, but after I've recovered I'm going to try yoga as well.
I'm a stay at home mom, so lots of times for me, I find just getting out of the house by myself helps a lot. Everyone is different, so like with meds, it can be a lot of trial and error.
Laura
Alex