ALS or something else

[4t1074]

32 Yr male.  Had prob with my throat for years and have not felt good for sometime in general.   Muscle twitching started, all over in all muscles below head at random. No atrophy or weakness. 9-26-06 went to see neuro, very concerned about ALS. Stated was not, No weakness/atrophy, reflexes good, neg bab. Put me on effexor-made me feel weird.  Went back to neuro 5 days later, very high ALS anxiety, due to feelings of my throat (feels like something in it), still swallow & breath easy, have to clear throat alot.  Bottom lip numb, speech different, noticable by me only, have to wipe spit off my lip all time now.  Put me on Lexapro, and he perf. a very short EMG in my left: arm, shoulder, hand muscles, he stated it was "quiet", so he didn't need to go further to my legs. Brain MRI - Neg. I have since went for op. w/ 2nd neuro, he looked at my upper extrem and feet, no weakness, no atrophy, stated in all his years in practice, everyone that pres to him with ALS, that by the time they got to doctor, the exam would have found weakness/atrophy. come back in 3 mos. I am now at a loss, because i feel very bad all the time, my twitches are still here, but have decreased, but are more focused in left arm,right thigh/leg, with occ. other places. My legs now feel if electricity is in them with "very rapid light twitches" ever 2 min in rt thigh. My rt. calf & lft arm area is sm than opposite. I have "attacks" where fingers cramp and back muscle is tight and severe fatigue. I still feel horrible all the time . What is yr opin on above and what should my next move be. I'm still conc w/ ALS

[johnflox]

What drugs have you taken in the past to treat your throat problems? Any antibiotic?
If you have taken cipro, levaquin, avelox, or similar ones then your symptoms could well be a delayed reaction to them, that can show up up to several months after taking the medicines.
There are dozens of other drugs that cause symptoms like the ones that you describe, that persist long after the treatment has been completed, for instance, most antimalarials, some inmunosupressors, and many more.
First of all you have to discard that you a negative reaction to a drug is surfacing now.