I would be very reluctant to jump at the diagnosis of a demyelinating disease on the basis of a single blood test showing an abnormality which is very non-specific.
The fact that you have had all the other tests you mention without any concrete evidence of demyelination makes it evem more unlikely.
Demyelinating diseases can affect both the central and peripheral nerves, the peripheral type causes peripheral neuropathy which would be detected on an EMG and the central types are rare in adults with the ecxception of MS and acute disseminated emcephalomyelitis which presents with an acute attack like MS and would be obvious on MRI scanning.
I think that the blood test should be repeated, but without further evidence to suggest a demyeinating disease I doubt if this is a very strong possibility.
Thank you for your prompt response. In addition to the blood test, the doctor is also considering my numerous symptoms of numbness, tingling, myoclonus, weakness with falling, pain in lower back, legs, neck and shoulders, urinary frequency/urgency and leakage, debilitating fatigue, the list goes on. The eye exam reveals abnormalities of the optic discs (tilting and cloudy), the neuro-opthal said it was suggestive of some sort of CNS disease, and called it a "peri optic neuritis". Neuro exam was essentially normal with the exception of weakness of my upper extremities and hyper-reflexes. My pcp didn't go into detail of specific names of other demylinating diseases that he thought it could be, thats why I posted the question on this forum. If any of this additional information helps and you have any more comments I would appreciate it, if not thank you for your time that you have taken to read this.
Thank you,
Kim W.