I am a 43 year old woman. I have a disease which is, as of yet, undiagnosed but it presents with tremors, severe back and spinal pain, as well as muscle pain/stiffness, all of which are exacerbated by cold weather and stress, making them unbearable. Other symptoms include balance problems and depression. With MRI, I had no legions and was ruled out for MS. I also had a negative RA for Lupus. Do you have any ideas as to what disease I am suffering from. Cold weather creates immediate and incredible intense pain, stiffness of muscles and tremors. Thank you for your time.