I am sorry if this is long but I think a little background is important. I am a 34 year old female and am a right leg amputee since I was 6 who has never been able to wear a prothesis. I have damaged my left knee from the stress of using this one leg always. I have had 2 scopes to clean up my knee, which at that time they found a 2.5 cm chondral defect on my medial femoral condyle and a smaller area on my patella. I still have severe pain when standing and walking. I am unable to bend or fully straighten my knee and sitting even is painful. I have done the shots and lots of theraphy. My OS did another MRI which has shown a full thickness chondral flap with kissing lesions on my medial femoral condyle. I don't know how large now but it was 2.5 cm in my last surgery. Because I am 34 and a amputee my os says I am too high risk for a replacement. So instead he wants to preform a microfracture and if it fails move onto knee replacement. He also feels I am not a canidate for any cartilage repair surgery because of the kissing lesions. I feel I have more damage on the tibia too because I have lots of pain below my knee cap and in my lower joint line behind my knee. My concern is that this surgery will fail for me because of the size of defect, the fact that this has been going on for 2 years, and the amount of other damage I have in other areas of my knee. I also fear it will fail because of the strict protocol you must follow after surgery being it will be near impossible for me to not bear weight, I am afraid I will over do it too early. Are there any options left for me? Is it possible the microfracture would work? I am at loss on what to do next, I know I can't just live unhappy and in pain for the rest of my life. I have 3 wondeful kids who depend on me.