I had a prescription for Ranitidine (prescription version of zantac 150) and it said to take it twice a day! I took it first thing in the morning then again before bed.
I take it every morning and sometimes twice a day once in the morning and once in the evening just don't take more than 2 in 24 hours I am 38 weeks pregnant
My Dr just put me on protonix because nothing else seemed to get rid of my heartburn. I take it morning and night and have been heartburn free since the 2nd day. Try tums for flare ups until you can talk to your Dr about possibly switching to something stronger
You can take it at night and take tums when you have a flare up that's what i do.